货号:A221634 同义名: 桦木脑 / Trochol;NSC 4644
Betulin, a natural product isolated and purified from the barks of Betula alba L., is a sterol regulatory element-binding protein (SREBP) inhibitor withIC50value of 14.5 μM in K562 cell line.
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描述 | Betulin, a natural product isolated and purified from the barks of Betula alba L., is a sterol regulatory element-binding protein (SREBP) inhibitor withIC50value of 14.5 μM in K562 cell line. |
NCT号 | 适应症或疾病 | 临床期 | 招募状态 | 预计完成时间 | 地点 |
NCT01657305 | Wounds | Phase 3 | Completed | - | Austria ... 展开 >> Medical University of Graz Graz, Austria Landesklinik für Dermatologie Salzburg, Austria Medical University Vienna Vienna, Austria Bulgaria University Multiprofile Hospital for Active Treatment-"Dr. Georgi Stranski" EAD Pleven, Bulgaria University Multiprofile Hospital for Active Treatment "Saint George" Plovdiv, Bulgaria Multiprofile Hospital for Active Treatment- Ruse Ruse, Bulgaria University Multiprofile Hospital for Active Treatment and Emergency Medicine "N.I.Pirogov" Sofia, Bulgaria University Multiprofile Hospital for Active Treatment-Varna at MMA-Sofia Varna, Bulgaria Czechia Universtity Hospital Brno Brno, Czechia University Hospital Olomouc Olomouc, Czechia Finland Päijät-Hämeen keskussairaala Lahti, Finland Satakunnan keskussairaala Pori, Finland Germany Trauma Hospital Berlin, Germany University Hospital Düsseldorf, Germany Essen University Hospital Essen, Germany University Hospital Frankfurt, Germany University Medical Center Freiburg, Germany University Medicine Greifswald Greifswald, Germany HELIOS Clinic Krefeld, Germany University Medical Center Mainz, Germany Klinikum rechts der Isar München, Germany Klinikum Offenbach am Main Offenbach, Germany Poland Univesity Hospital Gdansk Gdansk, Poland Samodzelny Publiczny Szpital Kliniczny Nr. 1 Lublin, Poland 收起 << |
NCT01657292 | - | Completed | - | - | |
NCT01657292 | Burns | Phase 3 | Completed | - | Germany ... 展开 >> Unfallkrankenhaus Berlin Berlin, Germany Berufsgenossenschaftliches Universitätsklinikum Bergmannsheil Bochum, Germany Universitätsklinikum Schleswig-Holstein Lübeck, Germany Sweden Linköping University Hospital Linköping, Sweden University Hospital Uppsala, Sweden Switzerland Centre Hospitalier Universitaire Vaudois Lausanne, Switzerland United Kingdom University Hospitals Birmingham NHS Foundation Trust Birmingham, United Kingdom Broomfield Hospital Chelmsford, United Kingdom Queen Victoria Hospital East Grinstead, United Kingdom 收起 << |
计算器 | ||||
存储液制备 | 1mg | 5mg | 10mg | |
1 mM 5 mM 10 mM |
2.26mL 0.45mL 0.23mL |
11.29mL 2.26mL 1.13mL |
22.59mL 4.52mL 2.26mL |
CAS号 | 473-98-3 |
分子式 | C30H50O2 |
分子量 | 442.717 |
别名 | 桦木脑 ;Trochol;NSC 4644;AI3-62999, Betulin, Betuline, Betulinol, Betulol, Trochol;betulinic alcohol;betuline;betulinol |
运输 | 蓝冰 |
存储条件 |
液体 -20°C:3-6个月-80°C:12个月 粉末 Sealed in dry,Room Temperature |
溶解度 |
DMSO: 3 mg/mL(6.78 mM),配合低频超声助溶,注意:DMSO长时间开封后,会吸水并导致溶解能力下降,请避免使用长期开封的DMSO |
动物实验配方 |
PO 0.5% CMC-Na 39 mg/mL suspension |