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白桦脂醇 /Betulin {[allProObj[0].p_purity_real_show]}

货号:A221634 同义名: 桦木脑 / Trochol;NSC 4644

Betulin, a natural product isolated and purified from the barks of Betula alba L., is a sterol regulatory element-binding protein (SREBP) inhibitor withIC50value of 14.5 μM in K562 cell line.

Betulin 化学结构 CAS号:473-98-3
Betulin 化学结构
CAS号:473-98-3
Betulin 3D分子结构
CAS号:473-98-3
Betulin 化学结构 CAS号:473-98-3
Betulin 3D分子结构 CAS号:473-98-3
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Betulin 纯度/质量文件 产品仅供科研

货号:A221634 标准纯度: {[allProObj[0].p_purity_real_show]}
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Betulin 生物活性

描述 Betulin, a natural product isolated and purified from the barks of Betula alba L., is a sterol regulatory element-binding protein (SREBP) inhibitor withIC50value of 14.5 μM in K562 cell line.

Betulin 临床研究

NCT号 适应症或疾病 临床期 招募状态 预计完成时间 地点
NCT01657305 Wounds Phase 3 Completed - Austria ... 展开 >> Medical University of Graz Graz, Austria Landesklinik für Dermatologie Salzburg, Austria Medical University Vienna Vienna, Austria Bulgaria University Multiprofile Hospital for Active Treatment-"Dr. Georgi Stranski" EAD Pleven, Bulgaria University Multiprofile Hospital for Active Treatment "Saint George" Plovdiv, Bulgaria Multiprofile Hospital for Active Treatment- Ruse Ruse, Bulgaria University Multiprofile Hospital for Active Treatment and Emergency Medicine "N.I.Pirogov" Sofia, Bulgaria University Multiprofile Hospital for Active Treatment-Varna at MMA-Sofia Varna, Bulgaria Czechia Universtity Hospital Brno Brno, Czechia University Hospital Olomouc Olomouc, Czechia Finland Päijät-Hämeen keskussairaala Lahti, Finland Satakunnan keskussairaala Pori, Finland Germany Trauma Hospital Berlin, Germany University Hospital Düsseldorf, Germany Essen University Hospital Essen, Germany University Hospital Frankfurt, Germany University Medical Center Freiburg, Germany University Medicine Greifswald Greifswald, Germany HELIOS Clinic Krefeld, Germany University Medical Center Mainz, Germany Klinikum rechts der Isar München, Germany Klinikum Offenbach am Main Offenbach, Germany Poland Univesity Hospital Gdansk Gdansk, Poland Samodzelny Publiczny Szpital Kliniczny Nr. 1 Lublin, Poland 收起 <<
NCT01657292 - Completed - -
NCT01657292 Burns Phase 3 Completed - Germany ... 展开 >> Unfallkrankenhaus Berlin Berlin, Germany Berufsgenossenschaftliches Universitätsklinikum Bergmannsheil Bochum, Germany Universitätsklinikum Schleswig-Holstein Lübeck, Germany Sweden Linköping University Hospital Linköping, Sweden University Hospital Uppsala, Sweden Switzerland Centre Hospitalier Universitaire Vaudois Lausanne, Switzerland United Kingdom University Hospitals Birmingham NHS Foundation Trust Birmingham, United Kingdom Broomfield Hospital Chelmsford, United Kingdom Queen Victoria Hospital East Grinstead, United Kingdom 收起 <<

Betulin 参考文献

[1]Krol SK, Kielbus M, et al. Comprehensive review on betulin as a potent anticancer agent. Biomed Res Int. 2015;2015:584189.

[2]Drag M, Surowiak P, et al. Comparision of the cytotoxic effects of birch bark extract, betulin and betulinic acid towards human gastric carcinoma and pancreatic carcinoma drug-sensitive and drug-resistant cell lines. Molecules. 2009 Apr 24;14(4):1639-51.

Betulin 实验方案

计算器
存储液制备 1mg 5mg 10mg

1 mM

5 mM

10 mM

2.26mL

0.45mL

0.23mL

11.29mL

2.26mL

1.13mL

22.59mL

4.52mL

2.26mL

Betulin 技术信息

CAS号473-98-3
分子式C30H50O2
分子量 442.717
别名 桦木脑 ;Trochol;NSC 4644;AI3-62999, Betulin, Betuline, Betulinol, Betulol, Trochol;betulinic alcohol;betuline;betulinol
运输蓝冰
存储条件

液体 -20°C:3-6个月-80°C:12个月

粉末 Sealed in dry,Room Temperature

溶解度

DMSO: 3 mg/mL(6.78 mM),配合低频超声助溶,注意:DMSO长时间开封后,会吸水并导致溶解能力下降,请避免使用长期开封的DMSO

动物实验配方

PO 0.5% CMC-Na 39 mg/mL suspension

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