Bedaquiline fumarate | R403323;TMC207 fumarate;TMC-207;R207910 fumarate | ATP Synthase | Antibacterial

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贝达喹啉富马酸盐 /Bedaquiline fumarate {[allProObj[0].p_purity_real_show]}

货号：A648653 同义名： R403323;TMC207 fumarate

Bedaquiline fumarate, a diarylquinoline antibiotic that targets ATP synthase, is effective for the treatment of Mycobacterium tuberculosis infections.

Bedaquiline fumarate 化学结构
CAS号：845533-86-0

Bedaquiline fumarate 3D分子结构
CAS号：845533-86-0

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Bedaquiline fumarate 纯度/质量文件产品仅供科研

货号：A648653 标准纯度： {[allProObj[0].p_purity_real_show]} 产品说明书

批次查询：批次纯度: COA SDS NMR HPLC CNMR LC-MS

全球学术期刊中引用的产品: • Cell Host Microbe, 2024. Ambeed. [ A163338 ]; • Cancer Res., 2024. Ambeed. [ A295334 ]; • J. Pharm. Investig., 2024. Ambeed. [ A221527 , A691302 , A272538 , A187261 ]; • J. Fungi, 2024, 10(11): 751. Ambeed. [ A796919 ]; • JBC, 2024, 107935. Ambeed. [ A194396 ]; 更多 >

Bedaquiline fumarate 生物活性

描述

Bedaquiline hinders the proliferation of TDR M. tuberculosis strains, showing MIC values within the range of 0.125 to 0.5 mg/LL^[1]. Bedaquiline demonstrates its highest efficacy against Mycobacterium avium among slowly growing mycobacteria (SGM), with MIC50 and MIC90 values of 0.03 and 16 mg/L, respectively. Among rapidly growing mycobacteria (RGM), both Mycobacterium abscessus subsp. abscessus (M. abscessus) and Mycobacterium abscessus subsp. massiliense (M. massiliense) appear to be more susceptible to bedaquiline compared to Mycobacterium fortuitum, with MIC50 and MIC90 values of 0.13 and >16 mg/L, respectively, for both species. Additionally, bedaquiline demonstrates moderate in vitro activity against non-tuberculous mycobacteria (NTM) species^[2]. Bedaquiline exhibits outstanding in vitro activity against Mycobacterium tuberculosis, including strains that are multidrug-resistant[3].

体外研究

Bedaquiline hinders the proliferation of TDR M. tuberculosis strains, showing MIC values within the range of 0.125 to 0.5 mg/LL^[1].

Bedaquiline demonstrates its highest efficacy against Mycobacterium avium among slowly growing mycobacteria (SGM), with MIC50 and MIC90 values of 0.03 and 16 mg/L, respectively. Among rapidly growing mycobacteria (RGM), both Mycobacterium abscessus subsp. abscessus (M. abscessus) and Mycobacterium abscessus subsp. massiliense (M. massiliense) appear to be more susceptible to bedaquiline compared to Mycobacterium fortuitum, with MIC50 and MIC90 values of 0.13 and >16 mg/L, respectively, for both species. Additionally, bedaquiline demonstrates moderate in vitro activity against non-tuberculous mycobacteria (NTM) species^[2].

Bedaquiline exhibits outstanding in vitro activity against Mycobacterium tuberculosis, including strains that are multidrug-resistant[3].

Bedaquiline fumarate 临床研究

NCT号	适应症或疾病	临床期	招募状态	预计完成时间	地点
NCT03625739	-		Recruiting	December 31, 2026	China ... 展开 >> Beijing Children's Hospital of Capital Medical University Recruiting Beijing, China Contact: Adong Shen, Master 13370115087 shenad16@hotmail.com 收起 <<
NCT03474198	Tuberculosis, Pulmonary	Phase 2 Phase 3	Recruiting	March 12, 2022	Philippines ... 展开 >> De La Salle Health Sciences Institute Not yet recruiting Manila, Philippines Lung Center Philippines Recruiting Manila, Philippines Philippines Tuberculosis Society Incorporated (PTSI) Not yet recruiting Manila, Philippines Tropical Disease Foundation Not yet recruiting Manila, Philippines Singapore National University Hospital Not yet recruiting Singapore, Singapore Thailand King Chulalongkorn Memorial Hospital Not yet recruiting Bangkok, Thailand 收起 <<
NCT00042289	HIV Infections	Phase 4	Recruiting	September 30, 2019	-

Bedaquiline fumarate 参考文献

[1]Ye X, et al. The identification of novel small-molecule inhibitors targeting WDR5-MLL1 interaction through fluorescence polarization based high-throughput screening. Bioorg Med Chem Lett. 2019 Feb 15;29(4):638-645.

[2]Chen X, et al. Targeting WD Repeat-Containing Protein 5 (WDR5): A Medicinal Chemistry Perspective. J Med Chem. 2021 Aug 12;64(15):10537-10556.

Bedaquiline fumarate 实验方案

计算器

存储液制备

1mg

5mg

10mg

1 mM

5 mM

10 mM

1.49mL

0.30mL

0.15mL

7.45mL

1.49mL

0.74mL

14.89mL

2.98mL

1.49mL

Bedaquiline fumarate 技术信息

CAS号	845533-86-0
分子式	C₃₆H₃₅BrN₂O₆
分子量	671.577

别名	R403323;TMC207 fumarate;TMC-207;R207910 fumarate
运输	蓝冰

存储条件

液体 -20°C:3-6个月-80°C:12个月

粉末 Inert atmosphere,Room Temperature

溶解度

DMSO: 105 mg/mL(156.35 mM)，配合低频超声助溶，注意：DMSO长时间开封后，会吸水并导致溶解能力下降，请避免使用长期开封的DMSO

动物实验配方

临床研究

NCT号	适应症或疾病	临床期	招募状态	预计完成时间	地点

NCT03625739	-		Recruiting	December 31, 2026	China ... 展开 >> Beijing Children's Hospital of Capital Medical University Recruiting Beijing, China Contact: Adong Shen, Master 13370115087 shenad16@hotmail.com 收起 <<
NCT03474198	Tuberculosis, Pulmonary	Phase 2 Phase 3	Recruiting	March 12, 2022	Philippines ... 展开 >> De La Salle Health Sciences Institute Not yet recruiting Manila, Philippines Lung Center Philippines Recruiting Manila, Philippines Philippines Tuberculosis Society Incorporated (PTSI) Not yet recruiting Manila, Philippines Tropical Disease Foundation Not yet recruiting Manila, Philippines Singapore National University Hospital Not yet recruiting Singapore, Singapore Thailand King Chulalongkorn Memorial Hospital Not yet recruiting Bangkok, Thailand 收起 <<
NCT00042289	HIV Infections	Phase 4	Recruiting	September 30, 2019	-
NCT03237182	Tuberculosis, Multidrug-Resist... 展开 >>ant 收起 <<	Phase 4	Recruiting	December 2021	South Africa ... 展开 >> King Dinuzulu Hospital Recruiting Durban, Kwa-Zulu Natal, South Africa Contact: Nesri Padayatchi, MBcHB 0312604550 nesri.padayatchi@caprisa.org Contact: Resha Boodhram, BTech 0828383651 resha.boodhram@caprisa.org 收起 <<
NCT02454205	Tuberculosis ... 展开 >>Multidrug Resistant Tuberculosis Extensively-drug Resistant Tuberculosis 收起 <<	Phase 2 Phase 3	Recruiting	January 2019	South Africa ... 展开 >> Brooklyn Chest Hospital Recruiting Cape Town, Western Cape, South Africa, 7441 Contact: Ali Esmail, MD 0214047654 ext 6119 a.esmail@uct.ac.za Contact: Lynelle Mottay, MD 0214046119 ext 6119 lynelle.mottay@uct.ac.za 收起 <<
NCT02409290	MDR-TB	Phase 3	Recruiting	December 2021	China ... 展开 >> Beijing Chest Hospital Not yet recruiting Beijing, China Wuhan Institute for TB control Not yet recruiting Wuhan, China Ethiopia Armauer Hanssen Research Institute Recruiting Addis Ababa, Ethiopia St. Peter's Tuberculosis Specializes Hospital Recruiting Addis Ababa, Ethiopia Georgia JSC National Center for Tuberculosis and Lung Diseases Recruiting Tbilisi, Georgia India BJ Medical College Civil Hospital Recruiting Ahmedabad, India The National Institute for Research in Tuberculosis Recruiting Chennai, India Indonesia RSUP Persahabatan Not yet recruiting Jakarta, Indonesia Moldova, Republic of Institute of Phthisiopneumology 'Chiril Draganiuc' Recruiting Chisinau, Moldova, Republic of Mongolia National Centre for Communicable Diseases Recruiting Ulaanbaatar, Mongolia South Africa King Dinizulu Hospital Recruiting Durban, South Africa Helen Joseph Hospital Recruiting Johannesburg, South Africa Sizwe Tropical Disease Hospital Active, not recruiting Johannesburg, South Africa Doris Goodwin Hospital Recruiting Pietermaritzburg, South Africa Empilweni TB Hospital Not yet recruiting Port Elizabeth, South Africa Uganda Makerere University Recruiting Kampala, Uganda Mulago National Referral Hospital Recruiting Kampala, Uganda Vietnam Pham Ngoc Thach Hospital Active, not recruiting Ho Chi Minh City, Vietnam 收起 <<
NCT02754765	Tuberculosis, Multidrug-Resist... 展开 >>ant 收起 <<	Phase 3	Recruiting	April 2021	Georgia ... 展开 >> National Center for Tuberculosis and Lung Diseases Recruiting Tbilisi, Georgia, 0101 Contact: Nino Kiria, MD msff-tbilisi-endtb@paris.msf.org Principal Investigator: Nana Kiria, MD Kazakhstan National Center for Tuberculosis Problems Recruiting Almaty, Kazakhstan Contact: Kanat Khazhidinov, MD kkhazhidinov@pih.org Principal Investigator: Elmira Berikova, MD Kyrgyzstan Osh Oblast Tuberculosis Hospital Not yet recruiting Osh, Kyrgyzstan Contact: Arnol Samiev, MD msfch-osh-tb@geneva.msf.org Principal Investigator: Kauk Galina Vladimirovna, MD Lesotho Partners In Health Lesostho Recruiting Maseru, Lesotho Contact: Sesomo Mohale smohale@pih.org Principal Investigator: Lawrence Oyewusi, MBBS Peru Socios En Salud Recruiting Lima, Peru Contact: Fanny Garcia Velarde fgarcia_ses@pih.org Principal Investigator: Leo Lecca, MD South Africa Medecins Sans Frontieres Belgium Recruiting Khayelitsha, South Africa, 7784 Contact: Jared Borain msfocb-khayelitsha-endtb@brussels.msf.org Principal Investigator: Sean Wasserman, MD 收起 <<
NCT03259269	-		Recruiting	September 30, 2020	Armenia ... 展开 >> National Treatment Centre for Tuberculosis, Abovian, Armenia Recruiting Abovyan, Armenia Contact: Naira Khachatryan, MD msff-erevan-medco@paris.msf.org Principal Investigator: Armen Hayrapetyan, MD Bangladesh National Institute of Diseases of the Chest and Hospital (NIDCH), Dhaka Recruiting Dhaka, Bangladesh Contact: Hamidah Hussain, MBBS, MSc hamidah.hussain@irdresearch.org Contact: Manzur ul-Alam, MD manzur.ulalam@irdresearch.org Belarus Republican Research and Practical Centre for Pulmonology and Tuberculosis Recruiting Minsk, Belarus, 220053 Contact: Yoseph Tassew, MD russia-medco@oca.msf.org Principal Investigator: Alena Skrahina, MD, PhD, DSc Ethiopia Bishoftu Hospital Recruiting Bishoftu, Ethiopia Contact: Andargachew Kumsa, MD AKumsa@pih.org Georgia National Center for Tuberculosis and Lung Diseases Recruiting Tbilisi, Georgia, 0101 Contact: Tinatin Kotrikadze, MD msff-tbilisi-medco@paris.msf.org Principal Investigator: Zara Avaliani, MPH, PhD Indonesia RS Islam Jakarta Cempaka Putih Not yet recruiting Jakarta, Indonesia Contact: Fauziah Asnely Putri, MD, MPH fauziah.putri@irdresearch.org Kazakhstan National Research Center for Phthisionpulmonology Recruiting Almaty, Kazakhstan, 050010 Contact: Yerkebulan Algozhin, MD ealgozhin@pih.org Principal Investigator: Elmira Berikova, MPH Kenya MSF Tuberculosis clinic, Mathare, Nairobi, Kenya Recruiting Nairobi, Kenya Contact: Stephen Wanjala, MD msff-nairobi-medco@paris.msf.org Principal Investigator: Maureen Kamene, MD, MBCHB Kyrgyzstan Kara-Suu District TB hospital Recruiting Kara-Suu, Kyrgyzstan Contact: Hayk Karakozian, MD MSFCH-Kyrgyzstan-Medco@geneva.msf.org Principal Investigator: Kadyrov Abdullaat, MD, PhD Lesotho Botshabelo Hospital Recruiting Maseru, Lesotho Contact: Kwonjune Seung, MD kjseung@pih.org Myanmar Aung San Tuberculosis Hospital Not yet recruiting Yangon, Myanmar Contact: Jarmila Kliescikova, MD myanmar-medco@oca.msf.org Principal Investigator: Si Tu Aung, MD Pakistan The Indus Hospital, Karachi Recruiting Karachi, Pakistan Contact: Rabia Mashkoor, MD rabia.mashkoor@ghd.ihn.org.pk Principal Investigator: Sana Adnan, MBBS, MSPH Institute of Chest Diseases, Kotri Recruiting Kotri, Pakistan Contact: Rabia Mashkoor, MD rabia.mashkoor@ghd.ihn.org.pk Principal Investigator: Sana Adnan, MBBS, MSPH Gulab Devi Chest Hospital, Lahore Recruiting Lahore, Pakistan Contact: Rabia Mashkoor, MD rabia.mashkoor@ghd.ihn.org.pk Principal Investigator: Sana Adnan, MBBS, MSPH Peru Socios en Salud Not yet recruiting Carabayllo, Peru Contact: Carmen Contreras, BS ccontreras_SES@pih.org Principal Investigator: Leonid Lecca, MD South Africa King Dinuzulu Hospital Recruiting Durban, South Africa Contact: Munira Khan, MBCHB munira.khan@irdresearch.org 收起 <<
NCT01215851	Pulmonary Tuberculosis	Phase 2	Completed	-	South Africa ... 展开 >> Centre for Tuberculosis Research Innovation, UCT Lung Institute Cape Town, South Africa, 7700 Task Applied Science, Karl Bremer Hospital Cape Town, South Africa 收起 <<
NCT03338621	Tuberculosis, Pulmonary ... 展开 >> Tuberculosis, Multidrug-Resistant Tuberculosis, MDR Tuberculosis Drug-Resistant Tuberculosis 收起 <<	Phase 2	Recruiting	January 31, 2022	Georgia ... 展开 >> National Center for Tuberculosis and Lung Diseases Recruiting Tbilisi, Georgia, 0101 Contact: Marike Eristavi, MD +99 559 954 0393 ma.eristavi@gmail.com Contact: Nestan Tukvadze 收起 <<
NCT01691534	Pulmonary Tuberculosis	Phase 2	Completed	-	South Africa ... 展开 >> Centre for Tuberculosis Research Innovation, UCT Lung Institute Cape Town, South Africa Task Applied Science, Karl Bremer Hospita Cape Town, South Africa 收起 <<
NCT01691534	-		Completed	-	-
NCT02589782	Tuberculosis, Multidrug-Resist... 展开 >>ant Extensively Drug-Resistant Tuberculosis Tuberculosis, Pulmonary 收起 <<	Phase 2 Phase 3	Recruiting	March 2021	Belarus ... 展开 >> Republican Scientific and Practical Centre for Pulmonology and Tuberculosis hospital Recruiting Minsk, Belarus Contact: Animesh Sinha, MD minsk-ct-mtl@oca.msf.org Principal Investigator: Alena Skrahina, MD South Africa Doris Goodwin Hospital Recruiting Pietermaritzburg, KwaZulu Natal, South Africa Contact: Suzanne Staples s.staples@thinksa.org.za Principal Investigator: Ronelle Moodliar, MBBS, MMed Don McKenzie Hospital Not yet recruiting Durban, KwaZulu-Natal, South Africa Contact: Suzanne Staples s.staples@thinksa.org.za Principal Investigator: Ronelle Moodliar, MBBS,MMed Uzbekistan Republican TB Hospital No. 2 Recruiting Nukus, Karakalpakstan, Uzbekistan Contact: Timur Gilmanov NukusCT-crc@oca.msf.org Principal Investigator: Tigay N Zinaida, MD Sh Alimov Republican Specialised Scientific-Practical Medical Centre for Phthysiology and Pulmonology Hospital Not yet recruiting Tashkent, Uzbekistan Contact: Viktoria Prymaka Principal Investigator: Irina Liverko, MD 收起 <<
NCT03086486	Tuberculosis, Pulmonary ... 展开 >> Tuberculosis, Multidrug-Resistant Tuberculosis, MDR Tuberculosis Extensively Drug-Resistant Tuberculosis Pre-XDR-TB 收起 <<	Phase 3	Recruiting	January 2022	Georgia ... 展开 >> National Center for Tuberculosis and Lung Diseases Recruiting Tbilisi, Georgia, 0101 Contact: Lali Mikiashvili Principal Investigator: Lali Mikiashvili Moldova, Republic of Institute of Phthisiopneumology Chiril Draganiuc Not yet recruiting Chisinau, Moldova, Republic of, 2025 Contact: Elena Tudor, MD Principal Investigator: Elena Tudor, MD Russian Federation Central TB Research Institute of the Federal Agency of Scientific Organizations Moscow Not yet recruiting Moscow, Russian Federation, 107564 Contact: Tatevik Bagdasaryan Principal Investigator: Tatevik Bagdasaryan Research Institute of Phthisiopulmonology of I.M. Sechenov First Moscow State Medical University Not yet recruiting Moscow, Russian Federation Contact: Anastasia Samoilova Principal Investigator: Anastasia Samoilova FSBI "Saint-Petersburg Research Institute of Phthisiopulmonology" Recruiting Saint Petersburg, Russian Federation, 191036 Contact: Petr Yablonskiy, MD Principal Investigator: Petr Yablonskiy, MD Ural Research Institute of Phthisiopulmonology Not yet recruiting Yekaterinburg, Russian Federation, 620039 Contact: Sergey Skornyakov, MD Principal Investigator: Sergey Skornyakov, MD South Africa Tshepong Hospital Recruiting Klerksdorp, North - West, South Africa, 2574 Contact: Ebrahim Variava Principal Investigator: Ebrahim Variava King DinuZulu Hospital Complex Recruiting Durban, South Africa, 4015 Contact: Nosipho Ngubane Principal Investigator: Nosipho Ngubane Clinical HIV Research Unit (CHRU) Sizwe Tropical Diseases Hospital Recruiting Johannesburg, South Africa, 2131 Contact: Pauline Howell, MD Principal Investigator: Pauline Howell, MD Empilweni TB Hospital Not yet recruiting Johannesburg, South Africa, 2194 Contact: Francesca Conradie, MBBS Principal Investigator: Francesca Conradie, MBBS 收起 <<
NCT01215851	-		Completed	-	-
NCT01600963	Multi-drug Resistant Tuberculo... 展开 >>sis 收起 <<	Phase 3	Withdrawn(PhIII program revise... 展开 >>d; TMC207-C210 cancelled) 收起 <<	November 2022	-
NCT00946842	Healthy	Phase 1	Completed	-	-
NCT02193776	Tuberculosis	Phase 2	Completed	-	South Africa ... 展开 >> The Aurum Institute: Tembisa Hospital Tembisa, Gauteng, South Africa, 1632 Klerksdorp Tshepong Hospital Jouberton, Klerksdorp, South Africa, 2570 TASK Applied Science Cape Town, South Africa, 7531 University of Cape Town Lung Institute (Pty) Ltd Cape Town, South Africa, 7937 THINK: Tuberculosis & HIV Investigative Network of KwaZulu-Natal Durban, South Africa CHRU Themba Lethu Clinic Johannesburg, South Africa University of Witwatersrand, Clinical HIV Research Unit (CHRU), Helen Joseph Hospital Johannesburg, South Africa Tanzania Ifakara Health Institute Bagamoyo, Tanzania NIMR-Mbeya Medical Research Centre (MMRC) Mbeya, Tanzania Uganda Uganda Case Western Reserve University Research Collaboration Kampala, Uganda 收起 <<
NCT00449644	-		Completed	-	-
NCT02583048	Tuberculosis ... 展开 >>HIV Infections 收起 <<	Phase 2	Active, not recruiting	April 27, 2020	Peru ... 展开 >> Barranco CRS Lima, Peru, 15063 South Africa Task Applied Science (TASK) CRS Cape Town, Western Cape Province, South Africa, 7530 South African Tuberculosis Vaccine Initiative (SATVI) CRS Cape Town, Western Cape Province, South Africa, 7705 收起 <<
NCT01464762	-		-	-	Lithuania ... 展开 >> Vilnius, Lithuania Russian Federation Arkhangelsk, Russian Federation Moscow, Russian Federation Orel, Russian Federation Saint-Petersburg, Russian Federation 收起 <<
NCT00449644	Tuberculosis	Phase 2	Completed	-	Brazil ... 展开 >> Rio De Janeiro, Brazil India Chennai, India New Delhi, India Latvia Stopinu Region, Latvia Peru Lima, Peru Philippines Quezon City, Philippines Russian Federation Moscow, Russian Federation South Africa Bethelsdorp, South Africa Cape Town, South Africa Durban, South Africa George, South Africa Klerksdorp, South Africa Sandringham, South Africa Thailand Chiang Mai, Thailand Nakhon, Thailand Nonthaburi, Thailand 收起 <<
NCT01341184	Tuberculosis	Phase 1	Completed	-	United States, Ohio ... 展开 >> Case Western Reserve University - Case Medical Center - Infectious Disease & HIV Medicine Cleveland, Ohio, United States, 44106-1716 收起 <<
NCT01291563	Healthy Volunteer	Phase 1	Completed	-	-
NCT01215110	Pulmonary Tuberculosis	Phase 2	Completed	-	South Africa ... 展开 >> Karl Bremer Hospital Belville, Cape Town, South Africa, 7531 收起 <<
NCT02274389	-		Active, not recruiting	December 31, 2018	United States, North Carolina ... 展开 >> Raleigh, North Carolina, United States 收起 <<
NCT00523926	Tuberculosis	Phase 2	Completed	-	-
NCT00992069	Tuberculosis ... 展开 >>HIV 收起 <<	Phase 1	Completed	-	United States, California ... 展开 >> Ucsf Aids Crs San Francisco, California, United States, 94110 United States, Maryland Johns Hopkins Adult AIDS CRS Baltimore, Maryland, United States, 21287 United States, North Carolina Unc Aids Crs Chapel Hill, North Carolina, United States, 27514 United States, Ohio The Ohio State Univ. AIDS CRS Columbus, Ohio, United States, 43210 United States, Tennessee Vanderbilt Therapeutics CRS Nashville, Tennessee, United States, 37232-2582 收起 <<
NCT02333799	Pulmonary Tuberculosis	Phase 3	Active, not recruiting	October 2021	South Africa ... 展开 >> Task Applied Science - Brooklyn Chest Hospital Ysterplaat, Cape Town, South Africa, 7405 King DinuZulu Hospital Complex Sydenham, Durban, South Africa, 4001 Sizwe Tropical Disease Hospital Sandringham, Johannesburg, South Africa, 2131 THINK: Tuberculosis & HIV Investigative Network of KwaZulu-Natal (Durban) Pietermaritzburg, Kwazulu-Natal, South Africa, 3200 收起 <<
NCT02906007	Tuberculosis ... 展开 >>HIV Infections 收起 <<	Phase 1 Phase 2	Recruiting	January 31, 2022	Haiti ... 展开 >> Les Centres GHESKIO Clinical Research Site (GHESKIO-INLR) CRS Recruiting Port-au-Prince, Haiti, HT-6110 Contact: Cynthia Riviere, M.D. 509-22222241 criviere@gheskio.org India Byramjee Jeejeebhoy Medical College (BJMC) CRS Recruiting Pune, Maharashtra, India, 411001 Contact: Nishi Suryavanshi, Ph.D. 91-98-23248979 nishi@jhumitpune.com South Africa Sizwe CRS Recruiting Johannesburg, Gauteng, South Africa Contact: Katerina Selibas 27-11-8823912 kselibas@witshealth.co.za PHRU Matlosana CRS Recruiting Klerksdorp, North West Province, South Africa, 2574 Contact: Katlego Motlhaoleng 27-18-4063359 motlhaolengk@phru.co.za Desmond Tutu TB Centre - Stellenbosch University (DTTC-SU) CRS Recruiting Cape Town, Western Cape Province, South Africa, 7505 Contact: Frieda A. Verheye-Dua 27-21-9389772 Frieda@sun.ac.za 收起 <<
NCT00910806	HIV Infections	Phase 1	Completed	-	South Africa ... 展开 >> George, South Africa 收起 <<
NCT00828529	Tuberculosis ... 展开 >>HIV 收起 <<	Phase 1	Completed	-	-
NCT00910871	Tuberculosis	Phase 2	Completed	-	-
NCT01012284	Moderate Hepatic Impairment	Phase 1	Completed	-	-
NCT00910871	-		Completed	-	-
NCT03032367	Tuberculosis	Early Phase 1	Completed	-	South Africa ... 展开 >> TASK Clinical Research Centre Bellville, Western Cape, South Africa, 7530 收起 <<
NCT02216331	Tuberculosis	Phase 1	Completed	-	United States, Nebraska ... 展开 >> Celerion (MDS Pharma Services) Lincoln, Nebraska, United States, 68502 收起 <<
NCT01803373	Healthy Biolo... 展开 >>gical Availability 收起 <<	Phase 1	Completed	-	Netherlands ... 展开 >> Groningen, Netherlands 收起 <<
NCT02365623	Tuberculosis, Multidrug-Resist... 展开 >>ant 收起 <<	Phase 2	Active, not recruiting	September 12, 2020	Japan ... 展开 >> Kiyose, Japan Sakai, Japan 收起 <<
NCT03384641	Leprosy, Multibacillary	Phase 2	Recruiting	July 7, 2021	Brazil ... 展开 >> Instituto Lauro de Souza Lima Recruiting Bauru, Brazil, 17034-971 Alfredo da Matta Foundation Not yet recruiting Manaus, Brazil, 69065-130 收起 <<
NCT02354014	Multidrug-Resistant Tuberculos... 展开 >>is 收起 <<	Phase 2	Recruiting	July 13, 2025	India ... 展开 >> B. J. Medical College & Civil Hospital Withdrawn Ahmedabad, India, 380 016 National Institute for Research in Tuberculosis (NIRT) Withdrawn Chennai, India, 600 031 National Institute of Tuberculosis and Respiratory Diseases (NITRD) Withdrawn New Delhi, India, 110 030 Philippines De La Salle Health Sciences Institute- DLSUMC Recruiting Dasmarinas, Philippines, 4114 Lung Center Of The Philippines Completed Quezon City, Philippines, 1100 Russian Federation First Moscow State Medical University n.a. I.M. Sechenov Recruiting Moscow, Russian Federation, 119991 South Africa THINK: Tuberculosis & HIV Investigative Network Recruiting Durban, South Africa, 4001 收起 <<
NCT01215110	-		Completed	-	-

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