BEC·HCl
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货号：A143511
同义名：
BEC (hydrochloride);BEC hydrochloride
BEC HCl is a competitive arginase inhibitor with Ki of 0.31 μM and 0.4-0.6 μM for Arginase II and rat Arginase I respectively.
BEC·HCl 化学结构
BEC·HCl 3D分子结构
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BEC·HCl 纯度/质量文件 产品仅供科研
货号：A143511
标准纯度：
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BEC·HCl 质控信息
BEC·HCl 生物活性
描述
BEC hydrochloride is a slow-binding and competitive Arginase II inhibitor with Ki of 0.31 μM and 30 nM at pH 7.5 and pH 9.5, respectively[3] [4] [5]
BEC·HCl 参考文献
[1] Steppan J, Ryoo S, et al. Arginase modulates myocardial contractility by a nitric oxide synthase 1-dependent mechanism. Proc Natl Acad Sci U S A. 2006 Mar 21;103(12):4759-64.
[2] Colleluori DM, Ash DE. Classical and slow-binding inhibitors of human type II arginase. Biochemistry. 2001 Aug 7;40(31):9356-62.
[3] Colleluori DM, Ash DE. Classical and slow-binding inhibitors of human type II arginase. Biochemistry. 2001 Aug 7;40(31):9356-62
[4] Ckless K, Lampert A, Reiss J, Kasahara D, Poynter ME, Irvin CG, Lundblad LK, Norton R, van der Vliet A, Janssen-Heininger YM. Inhibition of arginase activity enhances inflammation in mice with allergic airway disease, in association with increases in protein S-nitrosylation and tyrosine nitration. J Immunol. 2008 Sep 15;181(6):4255-64
[5] Lee SH, Ahn KM, Lee SY, Kim SS, Park HW. Blood Eosinophil Count as a Predictor of Lung Function Decline in Healthy Individuals. J Allergy Clin Immunol Pract. 2021 Jan;9(1):394-399.e1
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BEC·HCl 实验方案
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1mg
5mg
10mg
1 mM
5 mM
10 mM
4.36mL
0.87mL
0.44mL
21.79mL
4.36mL
2.18mL
43.57mL
8.71mL
4.36mL
BEC·HCl 技术信息
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