Ambeed.cn

首页 / / / / Aztreonam

氨曲南 /Aztreonam {[allProObj[0].p_purity_real_show]}

货号:A269798 同义名: SQ 26776;Urobactam

Aztreonam是一种合成的单环β-内酰胺类抗生素,主要用于治疗革兰氏阴性需氧细菌感染。

HazMat Fee +

There will be a HazMat fee per item when shipping a dangerous goods. The HazMat fee will be charged to your UPS/DHL/FedEx collect account or added to the invoice unless the package is shipped via Ground service. Ship by air in Excepted Quantity (each bottle), which is up to 1g/1mL for class 6.1 packing group I or II, and up to 25g/25ml for all other HazMat items.

Type HazMat fee for 500 gram (Estimated)
Excepted Quantity USD 0.00
Limited Quantity USD 15-60
Inaccessible (Haz class 6.1), Domestic USD 80+
Inaccessible (Haz class 6.1), International USD 150+
Accessible (Haz class 3, 4, 5 or 8), Domestic USD 100+
Accessible (Haz class 3, 4, 5 or 8), International USD 200+
Aztreonam 化学结构 CAS号:78110-38-0
Aztreonam 化学结构
CAS号:78110-38-0
Aztreonam 3D分子结构
CAS号:78110-38-0
Aztreonam 化学结构 CAS号:78110-38-0
Aztreonam 3D分子结构 CAS号:78110-38-0
规格 价格 会员价 库存 数量
{[ item.pr_size ]}

{[ getRatePrice(item.pr_rmb, 1,1) ]}

{[ getRatePrice(item.pr_rmb_sale, 1,1) ]} {[ suihuo_tips(item.pr_tag_price) ]}

{[ getRatePrice(item.pr_rmb, 1,1) ]}

{[ getRatePrice(item.pr_rmb,item.pr_rate,1) ]} {[ suihuo_tips(item.pr_tag_price) ]}
{[ getRatePrice(item.pr_rmb, 1,1) ]}{[ suihuo_tips(item.pr_tag_price) ]} {[ getRatePrice(item.pr_rmb_sale, 1,1) ]} {[ getRatePrice(item.pr_rmb,item.pr_rate,item.mem_rate) ]} {[ getRatePrice(item.pr_rmb,1,item.mem_rate) ]} 现货 咨询 - +
购物车0 收藏 询单

Aztreonam 纯度/质量文件 产品仅供科研

货号:A269798 标准纯度: {[allProObj[0].p_purity_real_show]}
批次查询: 批次纯度:

全球学术期刊中引用的产品

JMC, 2024. Ambeed. [ A919389 , A918471 , A995972 ]
Anal. Chem., 2024, 96(50): 19947-19954. Ambeed. [ A261947 , A1165388 ]
ACS Biomater. Sci. Eng., 2024. Ambeed. [ A220462 ]
ACS Biomater. Sci. Eng., 2024. Ambeed. [ A165235 , A110205 ]
Pharmaceutics, 2024, 16(12): 1546. Ambeed. [ A272538 , A187261 , A691302 , A506702 ]
更多 >

Aztreonam 生物活性

描述 Aztreonam is a new, totally synthetic beta-lactamase agent--the first monobactam. It is highly resistant to hydrolytic inactivation caused by plasmid-mediated (except PSE-2 enzyme found in some Pseudomonas species) or chromosomally mediated beta-lactamases (except for K1 produced by rare strains of Klebsiella oxytoca). The drug exhibits directed antibacterial activity against gram-negative organisms and is effective as monotherapy against most Enterobacteriaceae and Hemophilus and Neisseria species, including beta-lactamase-producing strains; it is not active against anaerobes or gram-positive organisms[3]. In polymicrobial infections or when used for empiric therapy, aztreonam must be combined with other antimicrobial agents active against gram-positive and anaerobic species. Overuse of aztreonam should be avoided to prevent the emergence of resistant P. aeruginosa strains. Except in the treatment of P. aeruginosa infections, aztreonam should not be added to beta-lactam regimens for additional gram-negative[4]. It can be used as a single agent for the treatment of upper urinary tract infections caused by organisms resistant to the cephalosporins and ampicillin. It also can be administered in combination with a drug such as clindamycin for treatment of pelvic inflammatory disease or postoperative pelvic infections[5].

Aztreonam 临床研究

NCT号 适应症或疾病 临床期 招募状态 预计完成时间 地点
NCT03440918 Sepsis Procal... 展开 >>citonin Antimicrobial Stewardship 收起 << Not Applicable Recruiting May 2019 United States, Tennessee ... 展开 >> Vanderbilt University Medical Center Recruiting Nashville, Tennessee, United States, 37232 收起 <<
NCT02685930 - Completed - United States, Missouri ... 展开 >> Barnes-Jewish Hospital Saint Louis, Missouri, United States, 63110 收起 <<
NCT03078010 Intestinal Microbiome ... 展开 >> Febrile Neutropenia 收起 << Phase 2 Recruiting February 2019 United States, New York ... 展开 >> Memorial Sloan Kettering Cancer Center Recruiting New York, New York, United States, 10065 Contact: Boglarka Gyurkocza, MD    212-639-2860       Contact: Susan Seo, MD    212-639-3151 收起 <<

Aztreonam 参考文献

[1]Charak BS, Louie R, et al. The effect of amphotericin B, aztreonam, imipenem and cephalosporins on the bone marrow progenitor cell activity. J Antimicrob Chemother. 1991 Jan;27(1):95-104.

[2]Sakurai Y, Yoshida Y, et al. Characteristics of aztreonam as a substrate, inhibitor and inducer for beta-lactamases. J Antibiot (Tokyo). 1990 Apr;43(4):403-10.

[3]Childs SJ, Bodey GP. Aztreonam. Pharmacotherapy. 1986;6(4):138-152

[4]Johnson DH, Cunha BA. Aztreonam. Med Clin North Am. 1995;79(4):733-743

[5]Clark P. Aztreonam. Obstet Gynecol Clin North Am. 1992;19(3):519-528

Aztreonam 实验方案

计算器
存储液制备 1mg 5mg 10mg

1 mM

5 mM

10 mM

2.30mL

0.46mL

0.23mL

11.48mL

2.30mL

1.15mL

22.97mL

4.59mL

2.30mL

Aztreonam 技术信息

CAS号78110-38-0
分子式C13H17N5O8S2
分子量 435.433
别名 SQ 26776;Urobactam
运输蓝冰
存储条件

In solvent -20°C:3-6个月-80°C:12个月

Pure form Keep in dark place,Sealed in dry,Store in freezer, under -20°C

溶解度

DMSO: 50 mg/mL(114.83 mM),配合低频超声助溶,注意:DMSO长时间开封后,会吸水并导致溶解能力下降,请避免使用长期开封的DMSO

H2O: 10 mg/mL(22.97 mM),配合低频超声助溶

动物实验配方
Ambeed 相关网站 Ambeed.cn Ambeed.com
Ambeed
关于我们
联系我们
资讯中心
网站地图
产品手册
  • 批次文件查询
  • 客户支持
    技术支持
    专业术语
    缩略词释义
    质量手册
    产品咨询
    计算器
    活动政策
    订购方法
    积分商城
    活动声明
    联系我们
    400-920-2911 sales@ambeed.cn tech@ambeed.cn
    Ambeed 只为有资质的科研机构、医药企业基于科学研究或药证申报的用途提供医药研发服务,不为任何个人或者非科研性质用途提供服务。