There will be a HazMat fee per item when shipping a dangerous goods. The HazMat fee will be charged to your UPS/DHL/FedEx collect account or added to the invoice unless the package is shipped via Ground service. Ship by air in Excepted Quantity (each bottle), which is up to 1g/1mL for class 6.1 packing group I or II, and up to 25g/25ml for all other HazMat items.
Type
HazMat fee for 500 gram (Estimated)
Excepted Quantity
USD 0.00
Limited Quantity
USD 15-60
Inaccessible (Haz class 6.1), Domestic
USD 80+
Inaccessible (Haz class 6.1), International
USD 150+
Accessible (Haz class 3, 4, 5 or 8), Domestic
USD 100+
Accessible (Haz class 3, 4, 5 or 8), International
Atosiban acetate (also known as RW22164 acetate or RWJ22164 acetate), a nonapeptide, functions as a competitive antagonist to vasopressin/oxytocin receptors and is an analog of desamino-oxytocin. It is primarily used as a tocolytic agent for the investigation of spontaneous preterm labor[1].
体内研究
The neuropeptides oxytocin and arginine vasopressin, which only differ by two amino acids, are both posterior pituitary hormones. Atosiban modulates the arginine vasopressin-induced physiological impacts on the cardiovascular and renal systems of the fetus and mother. In experiments involving late-gestation sheep, administering Atosiban for one hour does not result in any fetomaternal cardiovascular modifications[1].
Atosiban also inhibits the activation of neurons expressing oxytocin receptors in the parabrachial nucleus of mice[2].
体外研究
Atosiban prevents the release of IP3 triggered by oxytocin from the myometrial cell membrane, thereby reducing the release and influx of calcium within myometrial cells, and diminishing oxytocin-induced release of PGE and PGF from the decidua[1].
搜索
HazMat Fee +
