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Ampicillin Sodium {[allProObj[0].p_purity_real_show]}

货号:A307483 同义名: 氨苄青霉素钠 / D-(-)-α-Aminobenzylpenicillin sodium salt; Ampicillin(sodium salt)

Ampicillin Sodium是一种青霉素衍生物,作为广谱抗生素,可抗革兰氏阳性和阴性菌,使细菌细胞膜的内层转肽酶失活从而抑制细菌细胞壁的合成。Ampicillin Sodium也可用于分子生物学和组织培养(防止微生物污染和抗性筛选)。

HazMat Fee +

There will be a HazMat fee per item when shipping a dangerous goods. The HazMat fee will be charged to your UPS/DHL/FedEx collect account or added to the invoice unless the package is shipped via Ground service. Ship by air in Excepted Quantity (each bottle), which is up to 1g/1mL for class 6.1 packing group I or II, and up to 25g/25ml for all other HazMat items.

Type HazMat fee for 500 gram (Estimated)
Excepted Quantity USD 0.00
Limited Quantity USD 15-60
Inaccessible (Haz class 6.1), Domestic USD 80+
Inaccessible (Haz class 6.1), International USD 150+
Accessible (Haz class 3, 4, 5 or 8), Domestic USD 100+
Accessible (Haz class 3, 4, 5 or 8), International USD 200+
Ampicillin Sodium 化学结构 CAS号:69-52-3
Ampicillin Sodium 化学结构
CAS号:69-52-3
Ampicillin Sodium 3D分子结构
CAS号:69-52-3
Ampicillin Sodium 化学结构 CAS号:69-52-3
Ampicillin Sodium 3D分子结构 CAS号:69-52-3
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Ampicillin Sodium 纯度/质量文件 产品仅供科研

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Ampicillin Sodium 生物活性

描述 Ampicillin sodium is a member of β-lactam antibiotics (BLAs) used in treating a wide range of diseases and infections which were caused by both gram-positive and gram-negative bacteria in humans and animals, such as infections by sensitive bacteria, gastrointestinal and urinary tract infections, meningitis, and septicemia[3]. Ampicillin can dose-dependently protects neurons against ischemic brain injury[4]. In addition, hydrophilic ampicillin sodium can be developed as a transdermal delivery system with SA (sodium alginate) that is an alternative to intravenous administration and has minimal adverse effects[5].

Ampicillin Sodium 临床研究

NCT号 适应症或疾病 临床期 招募状态 预计完成时间 地点
NCT01892488 Chronic Obstructive Pulmonary ... 展开 >>Disease (COPD) 收起 << Phase 4 Recruiting September 2018 Germany ... 展开 >> Universitätsklinikum Aachen Recruiting Aachen, Germany HELIOS Klinikum Emil von Behring Berlin Recruiting Berlin, Germany Universitätsklinikum Dresden Recruiting Dresden, Germany Universitätsmedizin Greifswald Recruiting Greifswald, Germany Medizinische Hochschule Hannover Recruiting Hannover, Germany Principal Investigator: Tobias Welte, Prof. Dr.          Lungenfachklinik Immenhausen Recruiting Immenhausen, Germany Universitätsklinikum Jena Recruiting Jena, Germany Universitätsklinikum Schleswig-Holstein Campus Lübeck Recruiting Lübeck, Germany Brüderkrankenhaus St. Josef Paderborn Recruiting Paderborn, Germany Diakoniekrankenhaus Rotenburg Recruiting Rotenburg, Germany Krankenhaus Bethanien Solingen Recruiting Solingen, Germany 收起 <<
NCT01975493 - Active, not recruiting June 2018 United Kingdom ... 展开 >> Royal Cornwall Hospitals NHS Trust Truro, Cornwall, United Kingdom, TR1 3LJ Taunton and Somerset NHS Foundation Trust Taunton, Somerset, United Kingdom, TA1 5DA University Hospitals Coventry and Warwickshire NHS Trust Coventry, United Kingdom, CV2 2DX Alder Hey Children's Hospital Liverpool, United Kingdom, L12 2AP Liverpool Women's Hospital Liverpool, United Kingdom, L8 7SS St George's Hospital London, United Kingdom, SW17 0QT Great Ormond Street Hospital London, United Kingdom, WC1N 3JH John Radcliffe Hospital Oxford, United Kingdom, OX3 9DU Queen Alexandra Hospital Portsmouth, United Kingdom, PO6 3LY 收起 <<
NCT03113344 - Recruiting December 31, 2025 China ... 展开 >> Beijing Children's Hospital of Capital Medical University Recruiting Beijing, China Contact: Adong Shen, Master    13370115087    shenad16@hotmail.com 收起 <<

Ampicillin Sodium 参考文献

[1]Lee KE, Cho KO, et al. The neuroprotective mechanism of ampicillin in a mouse model of transient forebrain ischemia. Korean J Physiol Pharmacol. 2016 Mar;20(2):185-92.

[2]Chopra SL, Dale DG, et al. Effect of Ampicillin on E. Coli of Swine Origin. Can J Comp Med Vet Sci. 1963 Sep;27(9):223-7.

[3]Wu N, Luo Z, Ge Y, Guo P, Du K, Tang W, Du W, Zeng A, Chang C, Fu Q. A novel surface molecularly imprinted polymer as the solid-phase extraction adsorbent for the selective determination of ampicillin sodium in milk and blood samples. J Pharm Anal. 2016 Jun;6(3):157-164.

[4]Lee KE, Cho KO, Choi YS, Kim SY. The neuroprotective mechanism of ampicillin in a mouse model of transient forebrain ischemia. Korean J Physiol Pharmacol. 2016 Mar;20(2):185-92.

[5]Bagyalakshmi J, Vamsikrishna RP, Manavalan R, Ravi TK, Manna PK. Formulation development and in vitro and in vivo evaluation of membrane-moderated transdermal systems of ampicillin sodium in ethanol: pH 4.7 buffer solvent system. AAPS PharmSciTech. 2007 Jan 26;8(1):7.

Ampicillin Sodium 实验方案

计算器
存储液制备 1mg 5mg 10mg

1 mM

5 mM

10 mM

2.69mL

0.54mL

0.27mL

13.46mL

2.69mL

1.35mL

26.93mL

5.39mL

2.69mL

Ampicillin Sodium 技术信息

CAS号69-52-3
分子式C16H18N3NaO4S
分子量 371.39
SMILES Code O=C([C@@H](C(C)(C)S[C@]1([H])[C@@H]2NC([C@H](N)C3=CC=CC=C3)=O)N1C2=O)[O-].[Na+]
MDL No. MFCD00064313
别名 氨苄青霉素钠 ;D-(-)-α-Aminobenzylpenicillin sodium salt; Ampicillin(sodium salt)
运输蓝冰
InChI Key KLOHDWPABZXLGI-YWUHCJSESA-M
Pubchem ID 23663979
存储条件

In solvent -20°C:3-6个月-80°C:12个月

Pure form Keep in dark place, inert atmosphere, 2-8°C

溶解方案

DMSO: 190 mg/mL(511.6 mM),配合低频超声助溶,注意:DMSO长时间开封后,会吸水并导致溶解能力下降,请避免使用长期开封的DMSO

H2O: 200 mg/mL(538.52 mM)

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