There will be a HazMat fee per item when shipping a dangerous goods. The HazMat fee will be charged to your UPS/DHL/FedEx collect account or added to the invoice unless the package is shipped via Ground service. Ship by air in Excepted Quantity (each bottle), which is up to 1g/1mL for class 6.1 packing group I or II, and up to 25g/25ml for all other HazMat items.
Type
HazMat fee for 500 gram (Estimated)
Excepted Quantity
USD 0.00
Limited Quantity
USD 15-60
Inaccessible (Haz class 6.1), Domestic
USD 80+
Inaccessible (Haz class 6.1), International
USD 150+
Accessible (Haz class 3, 4, 5 or 8), Domestic
USD 100+
Accessible (Haz class 3, 4, 5 or 8), International
3-Phenyltoxoflavin, derived from Toxoflavin, acts as an Hsp90 inhibitor, demonstrating a dissociation constant (KD) of 585 nM for Hsp90-TPR2A interaction. It exhibits anti-cancer properties[1][2].
体外研究
3-Phenyltoxoflavin (1 nM-100 μM; 4 days) suppresses BT474 cell proliferation in a concentration-dependent fashion, achieving an IC50 of 690 nM[1].
3-Phenyltoxoflavin (0.56 nM-100 μM; 2 hours) competes with a biotinylated Hsp90 peptide for TPR2A binding in a dose-dependent way[1].
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