R-IMPP is a cell-permeable inhibitor of the secretion of proprotein convertase subtilisin/kexin type 9 (PCSK9) with IC50 of 4.8 µM.

SBC-110736 is an inhibitor of proprotein convertase subtilisin kexin type 9 (PCSK9), lowering cholesterol levels in mice.

Pep 2-8 is a proprotein convertase subtilisin/kexin type 9 (PCSK9) inhibitor.

PF-06446846 is an orally active proprotein convertase subtilisin/kexin type 9 (PCSK9) inhibitor. PF-06446846 directly and selectively inhibits translation of PCSK9 by stalling 80S ribosomes near codon regions.

PF-06446846 HCl是一种选择性的 PCSK9 翻译抑制剂，能通过干扰 PCSK9 的合成来调节胆固醇水平。它在胆固醇代谢和心血管疾病研究中具有潜力。

Evolocumab是一种人源化IgG2单克隆抗体，通过与PCSK9结合来阻止其与LDL受体结合。Evolocumab具有用于高胆固醇血症研究的潜力。