Polyphyllin D, a natural product isolated and purified from the rhizomes of Paris yunnanensis Franch. with anti-angiongenic, toxic and anti-cancer effects, induces apoptosis via the mitochondrial apoptotic pathway as evidenced by decreased Bcl-2 expression levels, disruption of MMP and increased Bax, cytochrome C and cleaved-caspase-3 levels.

Polyphyllin B is extracted from natural herb Paris polyphylla that can be used in cancer treatment.

Polyphyllin II is a natural product isolated and purified from the rhizomes of Paris yunnanensis Franch. with hemostasis, expectorant, bacteriostasis, anticytotoxic, anti-pregnancy and sperm-killing effects.

Ergosta-7,22-dien-3-one is a natural product isolated and purified from Lasiosphaera fenzlii with cytotoxic and antiinflammatory effect.

Polyphyllin VI, a natural product isolated and purified from the rhizomes of Paris yunnanensis Franch. with hemostasis, expectorant, bacteriostasis, anticytotoxic, anti-pregnancy and sperm-killing effects.

Polyphyllin H is a natural product isolated and purified from the rhizomes of Paris yunnanensis Franch..