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BMS-P5 free base是一种特异性的PAD4抑制剂,能够阻断NET形成,适用于多发性骨髓瘤和相关肿瘤研究。
BB-Cl-amidine is a irreversible peptidylarginine deminase (PAD) inhibitor.
Cl-amidine is a peptidylarginine deminase (PAD) inhibitor, with an IC50 5.9±0.3 μM for PAD4.
GSK484 is a reversible and selective inhibitor of PAD4 with IC50 of 50 nM. GSK484 blocks the citrullination of PAD4 target proteins in human neutrophils and inhibits the formation of neutrophil extracellular traps in both mouse and human neutrophils.
GSK199 is a reversible inhibitor of PAD4 (IC50 = 200 nM) that binds to the low-calcium form of the enzyme and is selective for PAD4 over PAD1-3.
Tags: PAD | 表观遗传学 | Epigenetics | 肿瘤表观遗传和基因调控 | Tumor Epigenetics and Gene Regulation | PAD 相关产品
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