Methylophiopogonanone B, a natural product isolated and purified from the roots of Ophiopogon japonicus, induces cell morphological change and Rho activation via melanocyte dendrite retraction and stress fiber formation.

Neoruscogenin is a natural sapogenin isolated from Butcher’s broom (R. rhizoma) that can relieve chronic venous disorders.

Prosapogenin A, a natural product isolated and purified from the roots of Ophiopogon japonicus with anti-obesity and immunomodulating effect, exhibits cytotoxic activity against the cancer cell line K562 in vitro.

Ophiopogonanone A, a natural product isolated and purified from the tubers of Ophiopogon japonicus(Thunb) Ker-Gawl., has oxygen free radicals(OFRs) scavenging effects, and can scavenge hydroxyl radical(·OH) and hydrogen peroxide(H2O2) in vitro.

Isobonducellin, a natural product isolated and purified from the roots of Ophiopogon japonicus, exhibits potent cytotoxic activity in Jurkat and HepG2 cells, while moderate growth inhibition against Colon205 cells.

Methylophiopogonone B is a natural product from ophiopogon japonicus.

Ophiopogonanone F, a natural product isolated and purified from the tubers of Ophiopogon japonicus(Thunb) Ker-Gawl., can be used for preparing a drug for resisting hepatocellular injury.

3-(2,4-dihydroxybenzyl)-5-hydroxy-7,8-dimethoxy-6-methylchroman-4-one is a natural product isolated and purified from the fibrous root of Ophiopogon japonicus.

Ophiopogonanone C is a natural product isolated and purified from the tubers of Ophiopogon japonicus(Thunb) Ker-Gawl..

Ophiopogonanone E, a natural product isolated and purified from the tubers of Ophiopogon japonicus(Thunb) Ker-Gawl. with oxygen free radicals(OFRs) scavenging effects, can scavenge hydroxyl radical(·OH) and hydrogen peroxide(H2O2) in vitro.

Liriope muscari baily saponins C, a natural product isolated and purified from the roots of Liriope muscari, has an anti-thrombotic activity due to down-regulation of the increased mRNA expression levels of IL-6 and TF.

Ruscogenin, a natural product isolated and purified from the root of Ophiopogon japonicus with significant anti-inflammatory and anti-thrombotic activities, significantly attenuates LPS-induced acute lung injury (ALI )via inhibiting expressions of TF and iNOS and NF-κB p65 activation, protects the brain against ischemic damage caused by middle cerebral artery occlusion (MCAO) which may be through downregulation of NF-κB-mediated inflammatory responses, inhibits activation of neutrophil through cPLA 2 , PAK, Akt, MAPKs, cAMP, and PKA signaling pathways, and may attenuate high-fat diet (HFD)-induced steatohepatitis through downregulation of NF- κB-mediated inflammatory responses, reducing hepatic lipogenic gene expression, and upregulating proteins in β-oxidation pathway.