Methylene blue is a synthetic basic dye used in chromoendoscopy to identify dysplasia, or pre-cancerous lesions. It also can stain cells and tissues in research.It also works as a soluble guanylyl cyclase inhibitor.

Leucomethylene blue mesylate是美克蓝的常见还原形式，作为第二代tau蛋白聚集抑制剂，用于治疗阿尔茨海默病（AD）和额颞叶痴呆（frontotemporal dementia）。

CRANAD-28 is a blood brain barrier (BBB) penetrable two-photon imaging probe.

Sulforhodamine 101, a fluorescent dye (Ex ~586nm, Em ~606nm), is a selective astrocyte marker.