Arachidonic Acid is an unsaturated, essential fatty acid. It is found in animal and human fat as well as in the liver, brain, and glandular organs, and is a constituent of animal phosphatides. It is formed by the synthesis from dietary linoleic acid and is a precursor in the biosynthesis of prostaglandins, thromboxanes, and leukotrienes.

Cyclophosphamide is a nitrogen mustard alkylating agent used in the treatment of cancers and autoimmune disorders.

Doxorubicin HCl 是一种有效的 DNA 拓扑异构酶 I 和 II 抑制剂，IC50 分别为 0.8 μM 和 2.67 μM。Doxorubicin HCl 具有细胞毒性和诱导凋亡 (apoptosis) 和自噬的作用，是一种广泛应用于癌症治疗的化疗药物。

Reserpine is a naturally occuring brain-penetrant and irreversible VMAT (vesicular monoamine transporter 1 and 2) antagonist.

5-Fluorouracil is a potent antitumor agent that affects pyrimidine synthesis by inhibiting thymidylate synthetase thus depleting intracellular dTTP pools.

Cisplatin (CDDP) 是一种抗肿瘤化疗剂，通过与 DNA 交联引起癌细胞中的 DNA 损伤。Cisplatin 可激活铁死亡 (ferroptosis) 并诱导自噬 (autophagy)。

MPTP hydrochloride 是可透过血脑屏障的多巴胺 (dopamine) 神经毒素，用于诱导帕金森综合症模型。MPTP hydrochloride 是 MPP+ 的前体，可以诱导细胞凋亡 (apoptosis)。

(+)-Bicuculline is an antagonist of GABAA receptor with IC50 of 2 μM and also shows inhibition of Ca(2+)-activated potassium channels.