MNK1/2-IN-5是一种有效且选择性的 MNK1/2 抑制剂，用于研究。

DS12881479是一种有效的 Mnk1 选择性抑制剂，IC50 为 21 nM，可用于癌症研究。

CGP-57380 is a selective Mnk1 inhibitor with IC50 value of 2.2 μM.

eFT508 is a potent, highly selective MNK1 and MNK2 inhibitor with IC50 value of 1-2 nM.

SLV-2436 is a highly potent and ATP-competitive inhibitor of MNK1 and MNK2 with IC50s of 10.8  nM and 5.4 nM, respectively.

ETC-206 is a selective MNK1 and MNK2 inhibitor with IC50s of 64 nM and 86 nM, respectively.

HG-10-102-01 is a potent and selective inhibitor of wild-type LRRK2 (IC50=23.3 nM) and the G2019S mutant (IC50=3.2 nM)

Cercosporamide is a potent and selective Mnk inhibitor, and an orally bioavailable antifungal agent, suppresses phosphorylation of eIF4E and exhibits antileukemic effects.