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microRNA-21-IN-2是一种潜在的 miR-21 抑制剂,AC50 为 3.29 μM,可用于癌症研究。
PIN1 inhibitor API-1是一种选择性 PIN1 抑制剂,通过阻断 PIN1 的顺反异构化作用,恢复相关蛋白质的功能。它在肝癌和其他肿瘤研究中具有潜在的治疗价值。
Lin28-let-7a antagonist 1 shows a clear antagonistic effect against the Lin28-let-7a interaction with an IC50 of 4.03 μM for Lin28A-let-7a-1 interaction.
Skullcapflavone I, a natural product isolated and purified from the roots of Scutellaria baicalensis Georgi, selectively induces apoptosis in T-HSC/Cl-6 cells via caspase-3 and caspase-9 activation.
Cl-amidine is an irreversible pan-peptidylarginine deiminase (PAD) inhibitor with IC50 values of with IC50 values of 5.9 ± 0.3 μM, 0.8 ± 0.3 μM, 6.2 ± 1.0 μM for PAD4, PAD1 and PAD3, respectively.
SID 3712249 is an inhibitor of the biogenesis of microRNA-544 (miR-544).
Targapremir-210 is a potent miR-210 inhibitor with an IC50 of 200 nM in MDA-MB-231 cells. Targapremir-210 binds to the Dicer site of the miR-210 hairpin precursor. This interaction inhibits production of the mature miRNA.
Tags: 微RNA | MicroRNA | 表观遗传学 | Epigenetics | 外泌体 | Exosome | 肿瘤表观遗传和基因调控 | Tumor Epigenetics and Gene Regulation | 微RNA 相关产品
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