GRA Ex-25 is an inhibitor of glucagon receptor, with IC50 of 56 and 55 nM for rat and human glucagon receptors, respectively.

NNC-0640是一种有效的人类胰高血糖素受体 (GCGR) 阴性变构调节剂 (NAM)，IC₅₀ 值为 69.2 nM，适用于糖尿病及代谢紊乱相关的研究。

Glucagon is a peptide hormone, exhibits therapeutic potential for metabolic disease.

PF-06882961 是一种 GLP-1R 激动剂。在 II 期研究中，它作为 2 型糖尿病治疗的候选药物。

Lixisenatide is a glucagon-like peptide-1 (GLP-1) receptor agonist that can be used in the treatment of type 2 diabetes mellitus (T2DM).

Semaglutide is an analog of human GLP-1 with long-acting effect over the other GLP-1Ras.

BETP is an agonist of glucagon-like peptide-1 (GLP-1) receptor, with EC50s of 0.66 and 0.755 μM for human and rat GLP-1 receptor, respectively.

Exendin Fragment 9-39 is an antagonist of glucagon-like peptide-1 (GLP-1) receptor, and also acts as an inhibitor of glucosedependent insulinotropic polypeptide (GIP)-receptor binding.

Exendin-4 是一种 GLP-1 受体激动剂，具有降血糖和促胰岛素分泌的作用。Exendin-4 主要用于糖尿病和肥胖症的研究。

Teduglutide , an analog of glucagon-like peptide 2, improves intestinal rehabilitation by promoting mucosal growth and possibly by inhibiting gastric emptying and secretion, which in turn reduces intestinal losses and promotes intestinal absorption.

Ubiquitin Isopeptidase Inhibitor I, G5 is an apoptosome-independent caspase and apoptosis activator.

Liraglutide是一种胰高血糖素样肽-1（GLP-1）受体激动剂，常用于2型糖尿病的临床治疗。

Orforglipron是一种口服活性的GLP-1受体激动剂，具有促进胰岛素分泌和抑制食欲的作用，广泛用于糖尿病及肥胖相关的代谢疾病研究，其详细信息可参考专利WO2018056453A1中的化合物67。

Shanzhiside methylester是一种 GLP-1 受体激动剂，具有抗糖尿病和改善异常性痛觉的能力。它在代谢疾病和疼痛管理方面有研究前景。

Adomeglivant is a potent and selective glucagon receptor antagonist that is used in clinical trial for type 2 diabetes mellitus.

Glucagon receptor antagonists-4 is an selective antagonist of glucagon receptor.

GLP-1(7-37) is an insulinotropic peptide generated from the precursor peptide GLP-1(1-37).