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BI-3663 is a CRBN-recruiting PROTAC targeting on PTK2.
PROTAC FAK degrader 1 is a selective and potent PROTAC targeting on Fak with DC50 value of 3nM. It was generated by linking defactinib and VHL ligand.
FC-11 is a potent FAK-targeting PROTAC. FC-11 showed a rapid and reversible FAK degradation with a picomolar of DC50 in various cell lines in vitro, which imply that FAK-PROTACs could be useful as expand tools for studying functions of FAK in biological system and as potential therapeutic agents.
Tags: FAK/PROTAC(FAK/PROTAC) | PROTAC功能分子 | PROTAC Molecule | FAK/PROTAC(FAK/PROTAC) 相关产品
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