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(+)-Bicuculline is an antagonist of GABAA receptor with IC50 of 2 μM and also shows inhibition of Ca(2+)-activated potassium channels.
Kainic acid 是一种强效的兴奋毒素和离子型谷氨酸受体亚型的激动剂,能够诱发癫痫发作,广泛用于神经科学研究中的癫痫模型。
(-)-Bicuculline methochloride (l-Bicuculline methochloride) is a potent GABAA receptor antagonist. (-)-Bicuculline methochloride blocks afterhyperpolarizations (AHPs) mediated by Ca2+-activated K+ channels in various types of neurons[1].
5-Hydroxytryptophan is a naturally occurring amino acid which acts as a chemical precursor as well as a metabolic intermediate in the biosynthesis of the neurotransmitter serotonin.
Tags: 癫痫模型 | Epilepsy Model | 神经系统疾病模型 | Nervous System Disease Models | 癫痫模型 相关产品
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