α-Cyperone, a natural product isolated and purified from the hizomes of Cyperus rotundus L., is associated with the down-regulation of COX-2,IL-6,Nck-2,Cdc42 and Rac1, resulting in reduction of inflammation.

Kobusone is a natural product isolated and purified from the roots of Cyperus rotundus L..

Cyperotundone is isolated from the root of cyperus rotundus L..and often used for content determination.