AZD1981是一种高效的 CRTh2 拮抗剂，IC50 为 4 nM，具有高选择性，能抑制 DP2 和 PGD2 的结合。

AM211是一种强效、选择性的前列腺素 D2 受体 2 型拮抗剂，IC50 值为 4.9 nM。

AMG 853 is a potent dual CRTH2 and prostaglandin D2 (PGD2) receptor antagonist (IC50 values are 8 and 35 nM, respectively in plasma).

CAY 10471 is a potent, highly selective CRTH2/DP 2 receptor antagonist. CAY10471 binds to the human CRTH2/DP2, DP1, and TP receptors with Ki values of 0.6, 1200, and >10,000 nM. Cat#531655 is a racemic mixture of CAY10471.

Fevipiprant is a selective, potent, reversible competitive CRTh2 antagonist with an in vitro dissociation constant KD value of 1.1nM at the CRTh2 receptor and an IC50 value of 0.44 nM for inhibition of PGD2-induced eosinophil shape change in human whole blood.

MK-7246 is a potent and selective CRTH2 antagonist with Ki value of 2.5nM.

CRTh2 antagonist 1是 CRTh2 的拮抗剂，IC50 值为89 nM。