Nepetin是一种从菊科植物中提取的天然黄酮，IC50 对 IL-6、IL-8 和 MCP-1 的分泌分别为 4.43 μM、3.42 μM 和 4.17 μM，表现出显著的抗炎和抗氧化作用，用于炎症和神经疾病研究。

Kuromanin chloride (Chrysontemin)是从桑叶中提取的，可增加血糖水平并保持脂质代谢平衡以减少肥胖。Kuromanin chloride还抑制CD38酶活性。

Diosmetin-7-O-β-D-glucopyranoside是一种从菊花（Chrysanthemum morifolium）的花中分离纯化的天然产物，具有抗氧化活性。

Shionone, a natural product isolated and purified from the flower of Chrysanthemum morifolium, has anti-inflammatory effect, the mechanism is related to decrease the phosphorylation level of ERK1/2 protein and IκBα and the protein expression of i NOS, and can inhibit the activity of ubiquitin-specific protease 2 (USP2) and provide a lead compound for future development of USP2 inhibitors.

Handelin is a guaianolide dimer from Chrysanthemum boreale that has potent anti-inflammatory activity by down-regulating NF-κB signaling and pro-inflammatory cytokine production[1].