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全部(36) Antagonist(2)
Zavegepant is a highly potent, selective and structurally unique small molecule CGRP receptor antagonist.
BMS-927711 is a highly potent, oral calcitonin gene-related peptide (CGRP) receptor antagonist with a Ki value of 0.027 nM.
MK-3207 is a potent and orally bioavailable CGRP receptor antagonist (IC50= 0.12 nM; Ki value= 0.024 nM), showing highly selective versus human AM1, AM2, CTR, and AMY3.
Galcanezumab是一种人源化IgG4单克隆抗体,通过与CGRP结合来阻止其与受体结合。Galcanezumab具有用于偏头痛预防的潜力。
Calcitonin salmon is a calcium regulating hormone secreted from mammalian thyroid parafollicular cells and in non-mammalian species from the ultimobranchial gland.
Fremanezumab是一种人源化IgG2单克隆抗体,通过与CGRP结合来阻止其与受体结合。Fremanezumab具有用于偏头痛预防的潜力。
SUN-B 8155 is a non-peptide calcitonin agonist.
PHM 27 (human) is a potent agonist for the human calcitonin receptor with EC50 of 11 nM.
Tags: 降钙素基因相关肽受体 | CGRP Receptor | G蛋白偶联受体/G蛋白 | GPCR/G Protein | 神经信号通路 | Neuronal Signaling | 降钙素基因相关肽受体 相关产品
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