E3330 (APX-3330) 是一种直接的、口服活性的、选择性的 Ape-1（无嘌呤/无嘧啶核酸内切酶 1）/Ref-1（氧化还原因子 1）抑制剂。E3330 抑制 NF-κB、AP-1 和 HIF-1α 在胰腺癌组织中的活性，具有抗癌活性。

Aristolochic acid A是一种从马兜铃科植物（Aristolochia debilis Sieb. et Zucc.）中提取的天然产物，强烈引起卵巢成熟过程中通过抑制Akt磷酸化介导的凋亡抑制的毒性损伤。

1-Methyl-6-oxo-1,6-dihydropyridine-3-carboxylic acid是从Cordyceps bassiana中提取的化合物，这是一种具有抗氧化、抗癌、抗炎、抗糖尿病、抗肥胖、抗血管生成和抗痛觉作用的虫草种类。1-甲基-6-氧代-1,6-二氢吡啶-3-羧酸能够靶向阻断AP-1介导的荧光素酶活性，表明它具有抗炎功能。

Fargesin is a lignan from Magnolia fargesii, an oriental medicine used in the treatment of nasal congestion and sinusitis.

SR 11302 is an inhibitor of activator protein-1 (AP-1) transcription factor.

Fargesin, a natural product isolated and purified from Flos Magnoliae, exerts anti-inflammatory effects in THP-1 monocytes by suppressing PKC-dependent AP-1 and NF-ĸB signaling.

Methyllinderone is a natural product isolated and purified from the roots of Lindera aggregata(Sims) Kosterm, showing moderate to weak antifungal activities against various pathogenic fungi, and selectively inhibits the growth of H-ras-transformed rat-2 cell lines with a GI50 value of 0.3 mM.

CFM 4, the CARP-1 mimetic, can interfere with CARP-1 binding to APC-2, enhance CARP-1 expression and induces G2/M cell cycle arrest and apoptosis and suppresses cell growth in cancer cells.

PNRI-299 is a selective AP-1 transcription inhibitor with IC50 of 20 μM without affecting NF-kappaB transcription (up to 200 μM) or thioredoxin (up to 200 μM).

Torilin, a natural product isolated and purified from the fruits of Torilis japonica with anti-inflammatory, antimicrobial, anti-angiogenic, antitumor and hepatoprotective properties.