Rifabutin is an antibiotic used to treat tuberculosis and prevent and treat Mycobacterium avium complex, which works through inhibiting DNA-dependent RNA polymerase activity in susceptible cells.

Geldanamycin是一种Hsp90抑制剂，对多种革兰氏阳性和一些革兰氏阴性细菌具有抗菌活性，还表现出抗流感病毒H5N1的活性。

Rifampicin是一种强效的广谱抗生素，对细菌病原体有效，还具有抗流感和抗正痘病毒的活性。

Rifaximin is an RNA synthesis inhibitor by binding the β subunit of the bacterial DNA-dependent RNA polymerase, used to treat traveler's diarrhea caused by certain bacteria.