Swertiajaponin是一种酪氨酸酶抑制剂，能通过多重氢键和疏水作用与酪氨酸酶结合，IC₅₀ 值为 43.47 μM。该化合物通过抑制氧化应激介导的 MAPK/MITF 信号通路降低酪氨酸酶蛋白水平，具有抗黑色素生成和抗氧化活性，适用于皮肤研究。

Swertiamarine is a naturally occuring secoiridoid glycoside which could inhibit HMG-CoA reductase activity.

Sweroside, a natural product isolated and purified from the herbs of Swertia bimaculata with strong hepatoprotective, anti-osteoporotic, insulin-mimicking, and wound-healing effects, can inhibit potent melanogenesis in melan-a cells at 300uM without cytotoxicity, also decreases tyrosinase, tyrosinase-related protein-1 (TRP-1) and TRP-2 protein production in melan a cells.

Erythrocentaurin is a hepatitis B virus inhibitor.

Methylswertianin and bellidifolin from Swertia punicea Hemsl have an effect on anti-diabetic.

Angustin A is a natural product isolated and purified from Swertia angustifolia.

Angustin B is a natural product isolated and purified from plants.