Loganin is a naturally occuring iridoid glycoside with antioxidant, hepatoprotective and neuroprotective effects, as well as a COX-1 inhbitor with IC50 value of 3.55 µM, suppressing the formation of TNF-α, and diminishing the production of nitric oxide.

Loganetin is a natural product isolated and purified from the seeds of Strychnos nux-vomica.

Vomicine is a natural product isolated and purified from the seeds of Strychnos nux-vomica.