VO-Ohpic trihydrate是一种高效的PTEN抑制剂，IC50为46±10 nM。

SF1670是一种有效且特异的染色体10上同源缺失磷酸酶（PTEN）抑制剂。

Oroxin B, a natural product isolated and purified from the roots of Scutellaria baicalensis., can selectively induce tumor-suppressive ER stress and concurrently inhibit tumor-adaptive ER stress in B-lymphoma cells for effective anti-lymphoma therapy.

Afzelin is a natural product isolated and purified from the herbs of thesium chinense Turcz.

bpV(HOpic) shows selective inhitory effect on PTP and PTEN (IC50 = 14 nM) and acts as an insulin mimic. It also can prevent myocardial ischemia-reperfusion injury by enhancing PI3K/Akt signaling.

Potent PTEN inhibitor

Ginkgolic Acid C17:1 is natural product with effects on cytotoxic and inhibition of migration.