货号:A819809 同义名: 乌拉坦 / Ethyl carbamate;Carbamic acid ethyl ester
Urethane(乌拉坦)常用于肺腺瘤模型的构建,会导致小鼠KrasQ61L或KrasQ61R驱动突变,在广泛靶基因中表现出全基因组A>T或A>G突变,诱导肺肿瘤的发生。
There will be a HazMat fee per item when shipping a dangerous goods. The HazMat fee will be charged to your UPS/DHL/FedEx collect account or added to the invoice unless the package is shipped via Ground service. Ship by air in Excepted Quantity (each bottle), which is up to 1g/1mL for class 6.1 packing group I or II, and up to 25g/25ml for all other HazMat items.
Type | HazMat fee for 500 gram (Estimated) |
Excepted Quantity | USD 0.00 |
Limited Quantity | USD 15-60 |
Inaccessible (Haz class 6.1), Domestic | USD 80+ |
Inaccessible (Haz class 6.1), International | USD 150+ |
Accessible (Haz class 3, 4, 5 or 8), Domestic | USD 100+ |
Accessible (Haz class 3, 4, 5 or 8), International | USD 200+ |
规格 | 价格 | 会员价 | 库存 | 数量 | |||
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快速发货 顺丰冷链运输,1-2 天到达
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描述 | Urethane (Ethyl carbamate), the ethyl ester of carbamic acid, is a fermentation byproduct found in various food products and is known to inhibit the growth of bacteria, protozoa, sea urchin eggs, and plant tissues in vitro[1]. |
体内研究 | Urethane is utilized in animal research to create tumor models and has historically been used to induce hypnosis and narcosis in mammals, fish, and amphibians. When administered at anesthetic doses (1-1.2 g/kg body weight for rats), urethane is generally safe, causing minimal alterations in blood pressure, aortic blood flow, and blood-gas levels[1]. Additionally, at a dosage of 1g/kg IP (administered intraperitoneally), urethane arrests cell division in the crypt of liberkuhn cells in mice[1]. |
体外研究 | As a clastogen, urethane shows effectiveness in inducing sister chromatid exchanges in various cells and demonstrates variable results with cells in vitro, making it a useful clastogen in mammalian somatic cells in vivo[2]. |
Animal study | 肺肿瘤模型 动物:hPRDX4 转基因 (Tg) 和非转基因 C57BL/6 小鼠, 雄性,8 周龄。 给药:1 g/kg (在 100 μL 生理盐水中) ,腹腔注射 ,每周一次,持续 16 周或每隔一天一次,持续一周。 |
NCT号 | 适应症或疾病 | 临床期 | 招募状态 | 预计完成时间 | 地点 |
NCT00924508 | Eczema | Not Applicable | Terminated(Loss of Funding) | - | United States, California ... 展开 >> UCSF Psoriasis Skin and Treatment Center San Francisco, California, United States, 94118 收起 << |
NCT02136901 | Meniscectomy ... 展开 >>Osteoarthritis 收起 << | Not Applicable | Active, not recruiting | June 2020 | Belgium ... 展开 >> AZ Monica Antwerp, Belgium, BE-2018 France Centre Hospitalier de Versailles Le Chesnay CEDEX, France, F 78158 Germany Universitätsklinikum Freiburg Freiburg, Germany, 79106 University Hospital of Munich Munich, Germany, 81377 Universitätklinikum Regensburg Regensburg, Germany, 93042 Israel Ichilov Hospital Tel Aviv, Israel, 64239 Meuhedet HCO Tel-Aviv, Israel, 62038 Assaf Harofeh Medical Center Zerifin, Israel, 70300 Italy Ospedale Sacro Cuore - Don Calabria Negrar, Verona, Italy, 37024 Netherlands Academisch Ziekenhuis Maastricht Maastricht, Netherlands, 66202 Sweden Hallands Sjukhus Kungsbacka Kungsbacka, Halland, Sweden, SE-434 80 收起 << |
NCT01133327 | Carotid Artery Disease ... 展开 >> Carotid Stenosis Stroke 收起 << | Not Applicable | Completed | - | Belgium ... 展开 >> A.Z. Sint Blasius Dendermonde, East-Flanders, Belgium, 9200 Imelda Ziekenhuis Bonheiden, Belgium, B-9200 CHU Sart Tilman Liege, Belgium, B-400 Germany Königin Elisabeth Herzberge Berlin, Germany, D-10365 Klinikum Dortmund Dortmund, Germany, D-44137 Universitaetsklinikum Heidelberg Heidelberg, Germany, D69120 Park KH Leipzig, Germany, D-04289 Klinikum Neuperlach Munich Munich, Germany, D-81737 Radiologische Universitätklinik Tübingen, Germany, D-72076 Spain Hospital Juan Canalejo La Coruna, Spain, 15174 Complejo Hospitalario de Toledo Toledo, Spain, S-45004 收起 << |
计算器 | ||||
存储液制备 | 1mg | 5mg | 10mg | |
1 mM 5 mM 10 mM |
11.22mL 2.24mL 1.12mL |
56.12mL 11.22mL 5.61mL |
112.24mL 22.45mL 11.22mL |
CAS号 | 51-79-6 |
分子式 | C3H7NO2 |
分子量 | 89.093 |
别名 | 乌拉坦 ;Ethyl carbamate;Carbamic acid ethyl ester;NSC 746;Ethylurethane |
运输 | 蓝冰 |
存储条件 |
液体 -20°C:3-6个月-80°C:12个月 粉末 Sealed in dry,Room Temperature |
溶解度 |
DMSO: 105 mg/mL(1178.54 mM),配合低频超声助溶,注意:DMSO长时间开封后,会吸水并导致溶解能力下降,请避免使用长期开封的DMSO |
动物实验配方 |