货号:A976001 同义名: 托普霉素 / Nebramycin Factor 6;Deoxykanamycin B
Tobramycin is an aminoglycoside, broad-spectrum antibiotic produced by Streptomyces tenebrarius.
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描述 | Tobramycin is a new aminoglycoside antibiotic with a broad antibacterial spectrum in vitro, and pharmacokinetic properties similar to those for gentamicin. Like other aminoglycoside antibiotics, tobramycin is active in vitro in low concentrations against Staphylococcus aureus. The sensitivity of P. aeruginosa to tobramycin is influenced by the magnesium, and calcium content of the culture media whilst that of all species is reduced by sodium ions[2]. Aerosolized tobramycin 100 mg/ml solution delivered higher lung dose compared to tobramycin 40 mg/ml solution[3]. When tilmicosin is used to treat clinical outbreaks of M. gallisepticum in broilers, a dosing scheme of 20 mg tilmicosin/kg BW (body weight) for five successive days seems to be the most recommended scheme[4]. |
NCT号 | 适应症或疾病 | 临床期 | 招募状态 | 预计完成时间 | 地点 |
NCT02958514 | Dry Eye Syndrome | Not Applicable | Unknown | March 2017 | - |
NCT01319253 | - | Completed | - | United States, Indiana ... 展开 >> Indiana University Indianapolis, Indiana, United States, 46202 收起 << | |
NCT02334384 | Furunculosis | Phase 1 Phase 2 | Completed | - | United States, Virginia ... 展开 >> Sentara Norfolk General Hospital Norfolk, Virginia, United States, 23507 收起 << |
计算器 | ||||
存储液制备 | 1mg | 5mg | 10mg | |
1 mM 5 mM 10 mM |
2.14mL 0.43mL 0.21mL |
10.69mL 2.14mL 1.07mL |
21.39mL 4.28mL 2.14mL |
CAS号 | 32986-56-4 |
分子式 | C18H37N5O9 |
分子量 | 467.514 |
别名 | 托普霉素 ;Nebramycin Factor 6;Deoxykanamycin B;NSC 180514;Gernebcin;Distobram |
运输 | 蓝冰 |
存储条件 |
液体 -20°C:3-6个月-80°C:12个月 粉末 Keep in dark place,Inert atmosphere,2-8°C |
溶解度 |
DMSO: 2 mg/mL(4.28 mM),配合低频超声助溶,注意:DMSO长时间开封后,会吸水并导致溶解能力下降,请避免使用长期开封的DMSO H2O: 100 mg/mL(213.9 mM) |
动物实验配方 |