There will be a HazMat fee per item when shipping a dangerous goods. The HazMat fee will be charged to your UPS/DHL/FedEx collect account or added to the invoice unless the package is shipped via Ground service. Ship by air in Excepted Quantity (each bottle), which is up to 1g/1mL for class 6.1 packing group I or II, and up to 25g/25ml for all other HazMat items.
Type
HazMat fee for 500 gram (Estimated)
Excepted Quantity
USD 0.00
Limited Quantity
USD 15-60
Inaccessible (Haz class 6.1), Domestic
USD 80+
Inaccessible (Haz class 6.1), International
USD 150+
Accessible (Haz class 3, 4, 5 or 8), Domestic
USD 100+
Accessible (Haz class 3, 4, 5 or 8), International
Sacubitrilat (LBQ657) is characterized by its specific stereochemistry, making it a potent inhibitor (5 nM) of the neutral endopeptidase (NEP) through a comprehensive network of interactions at the enzyme's active site[1].
体内研究
The pharmacokinetic profiles of Sacubitrilat (LBQ657) was assessed following single oral doses of LCZ696 at either 400 or 1200 mg under fasting conditions. Sacubitrilat showed corresponding Tmax values of 2.07 and 3.05 hours. The maximum concentration (Cmax) of Sacubitrilat increases dose-proportionally, whereas Sacubitril and Valsartan show less than proportional increases between the doses[2].
体外研究
Sacubitrilat (LBQ657) is characterized by its specific stereochemistry, making it a potent inhibitor (5 nM) of the neutral endopeptidase (NEP) through a comprehensive network of interactions at the enzyme's active site[1].
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HazMat Fee +
