Lecirelin is a synthetic GnRH analogue which showed a great efficacy in the treatment of bovine ovarian follicular cysts.
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Type | HazMat fee for 500 gram (Estimated) |
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描述 | Lecirelin is a synthetic gonadotropin releasing hormone (GnRH) analogue which commonly used in the treatment of bovine ovarian follicular cysts. The treatment of choice is intramuscular administration of lecirelin. However, the epidural administration of lecirelin promoted the remission of follicular cysts and an improvement of reproductive parameters compared to intramuscular administration[2]. There was a significantly lower LH release after gonadorelin treatment compared to lecirelin at the doses of 25 or 50 μg and the buserelin treatment[3]. The percentage of disappearance of the dominant follicle (84.8% of ovulation and 4.3% of luteinization) after GnRH treatment was high (82% and 100%, for lecirelin at the doses of 25 and 50 μg respectively). Lecirelin, at the doses indicated for the induction of ovulation, is almost equally effective to induce the disappearance of the dominant follicle at Day 6 to 7 of the estrous cycle[3]. Lecirelin modulates the contractility of the bovine ovarian follicular wall; in basal conditions and after the addition of lecirelin, the strips from preovulatory follicles contract significantly more than strips from cysts[4]. |
计算器 | ||||
存储液制备 | 1mg | 5mg | 10mg | |
1 mM 5 mM 10 mM |
0.83mL 0.17mL 0.08mL |
4.13mL 0.83mL 0.41mL |
8.27mL 1.65mL 0.83mL |
CAS号 | 61012-19-9 |
分子式 | C59H84N16O12 |
分子量 | 1209.398 |
别名 | Lecirelin游离态 |
运输 | 蓝冰 |
存储条件 |
粉末 Keep in dark place,Sealed in dry,Store in freezer, under -20°C 液体 -20°C:3-6个月-80°C:12个月 |
溶解度 |
DMSO: 12 mg/mL(9.92 mM),配合低频超声,并水浴加热至45℃助溶,注意:DMSO长时间开封后,会吸水并导致溶解能力下降,请避免使用长期开封的DMSO H2O: 25 mg/mL(20.67 mM),配合低频超声助溶 |
动物实验配方 |