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L 152804 {[allProObj[0].p_purity_real_show]}

货号:A1058930 Ambeed 开学季,买赠积分,赢豪礼

L 152804 is a selective non-peptide neuropeptide Y Y5 receptor antagonist (Ki = 26 nM).

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L 152804 化学结构 CAS号:6508-43-6
L 152804 化学结构
CAS号:6508-43-6
L 152804 3D分子结构
CAS号:6508-43-6
L 152804 化学结构 CAS号:6508-43-6
L 152804 3D分子结构 CAS号:6508-43-6
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L 152804 纯度/质量文件 产品仅供科研

货号:A1058930 标准纯度: {[allProObj[0].p_purity_real_show]}
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L 152804 生物活性

描述 L 152804 is an orally active, selective neuropeptide Y5 receptor (NPY5-R) antagonist with a Ki value of 26 nM against hY5. L 152804 results in weight loss in diet-induced obese mice through modulation of food intake and energy expenditure[1][2].

L 152804 参考文献

[1]Kanatani A, et al. L-152,804: orally active and selective neuropeptide Y Y5 receptor antagonist. Biochem Biophys Res Commun. 2000 May 27;272(1):169-73.

[2]Mashiko S, et al. A pair-feeding study reveals that a Y5 antagonist causes weight loss in diet-induced obese mice by modulating food intake and energy expenditure. Mol Pharmacol. 2007 Feb;71(2):602-8. Epub 2006 Nov 14.

L 152804 实验方案

计算器
存储液制备 1mg 5mg 10mg

1 mM

5 mM

10 mM

2.73mL

0.55mL

0.27mL

13.64mL

2.73mL

1.36mL

27.29mL

5.46mL

2.73mL

L 152804 技术信息

CAS号6508-43-6
分子式C23H26O4
分子量 366.45
别名
运输蓝冰
存储条件

粉末 Sealed in dry,2-8°C

液体 -20°C:3-6个月-80°C:12个月

溶解度

DMSO: 120 mg/mL(327.47 mM),注意:DMSO长时间开封后,会吸水并导致溶解能力下降,请避免使用长期开封的DMSO

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