Ambeed 大中华区 CN | ZH

中文 - ZH English - EN

Ambeed.cn

搜索

关键字搜索批量搜索

首页 收藏 购物车0
首页 /
抑制剂/激动剂
药物研究 抗生素和抗病毒
/
抗感染
药物分析 功能
/
药物标准品
Antibacterial 抗真菌抗生素
/ Imipenem monohydrate

亚胺培南一水物 /Imipenem monohydrate {[allProObj[0].p_purity_real_show]}

货号：A103901 同义名： 亚胺培南一水物 / N-Formimidoyl thienamycin monohydrate;MK0787 monohydrate

Imipenem monohydrate 是一种广谱 β-内酰胺类抗生素，对多种革兰氏阳性和阴性细菌具有高效杀菌作用，MIC 值为 0.06-0.5 μg/mL。Imipenem monohydrate 主要用于严重细菌感染的治疗研究。

HazMat Fee +

There will be a HazMat fee per item when shipping a dangerous goods. The HazMat fee will be charged to your UPS/DHL/FedEx collect account or added to the invoice unless the package is shipped via Ground service. Ship by air in Excepted Quantity (each bottle), which is up to 1g/1mL for class 6.1 packing group I or II, and up to 25g/25ml for all other HazMat items.

Type HazMat fee for 500 gram (Estimated)
Excepted Quantity USD 0.00
Limited Quantity USD 15-60
Inaccessible (Haz class 6.1), Domestic USD 80+
Inaccessible (Haz class 6.1), International USD 150+
Accessible (Haz class 3, 4, 5 or 8), Domestic USD 100+
Accessible (Haz class 3, 4, 5 or 8), International USD 200+
Imipenem monohydrate 化学结构 CAS号：74431-23-5
Imipenem monohydrate 化学结构
CAS号：74431-23-5
Imipenem monohydrate 3D分子结构
CAS号：74431-23-5
Imipenem monohydrate 化学结构 CAS号：74431-23-5
Imipenem monohydrate 3D分子结构 CAS号：74431-23-5
规格 价格 会员价 库存 数量
{[ item.pr_size ]}

{[ getRatePrice(item.pr_rmb, 1,1) ]}

{[ getRatePrice(item.pr_rmb_sale, 1,1) ]} {[ suihuo_tips(item.pr_am, item.pr_size) ]}

{[ getRatePrice(item.pr_rmb, 1,1) ]}

{[ getRatePrice(item.pr_rmb,item.pr_rate,1) ]} {[ suihuo_tips(item.pr_am, item.pr_size) ]} 		{[ getRatePrice(item.pr_rmb, 1,1) ]}{[ suihuo_tips(item.pr_am, item.pr_size) ]} {[ getRatePrice(item.pr_rmb_sale, 1,1) ]} {[ getRatePrice(item.pr_rmb,item.pr_rate,item.mem_rate) ]} {[ getRatePrice(item.pr_rmb,1,item.mem_rate) ]} 现货 咨询 - +
购物车0 收藏 询单

Imipenem monohydrate 纯度/质量文件 产品仅供科研

货号：A103901 标准纯度： {[allProObj[0].p_purity_real_show]}
批次查询： 批次纯度:

全球学术期刊中引用的产品

• Cell Host Microbe, 2024. Ambeed. [ A163338 ]
• Cancer Res., 2024. Ambeed. [ A295334 ]
• J. Pharm. Investig., 2024. Ambeed. [ A221527 , A691302 , A272538 , A187261 ]
• J. Fungi, 2024, 10(11): 751. Ambeed. [ A796919 ]
• JBC, 2024, 107935. Ambeed. [ A194396 ]
更多 >

Imipenem monohydrate 生物活性

描述 Imipenem (Monohydrate) is the first of a new class of beta-lactam antibiotics, the carbapenems, to be released for clinical use. It has the broadest antibacterial activity of all antibiotics available for systemic use in humans. It is active against streptococci, methicillin-sensitive staphylococci, Neisseria, Haemophilus, anaerobes, and the common aerobic gram-negative nosocomial pathogens including Pseudomonas [3]. For combinations of imipenem and colistin, synergy was observed for the fourteen isolates with imipenem MICs of 16 μg/mL and one isolate with an imipenem MIC of 64 μg/mL[4]. Imipenem/cilastatin is generally well tolerated by adults and children, with local injection site events, gastrointestinal disturbances and dermatological reactions being the most common adverse events[5].

Imipenem monohydrate 临床研究

NCT号 适应症或疾病 临床期 招募状态 预计完成时间 地点
NCT01381549 Infections, Urinary Tract Phase 2 Terminated(Microbiological fin... 展开 >>dings of resistance on therapy in patients with complicated urinary tract infection) 收起 << - United States, California ... 展开 >> GSK Investigational Site Los Angeles, California, United States, 90033 United States, Iowa GSK Investigational Site Council Bluffs, Iowa, United States, 51503 United States, Kansas GSK Investigational Site Topeka, Kansas, United States, 66604 United States, Texas GSK Investigational Site Corsicana, Texas, United States, 75110 Canada, Quebec GSK Investigational Site Chicoutimi, Quebec, Canada, G7H 5H6 GSK Investigational Site Sherbrooke, Quebec, Canada, J1H 5N4 France GSK Investigational Site Suresnes, France, 92151 GSK Investigational Site Toulouse cedex 9, France, 31059 Greece GSK Investigational Site Athens, Greece, 11527 GSK Investigational Site Chaidari, Greece, 12462 GSK Investigational Site Goudi, Athens, Greece, 11527 GSK Investigational Site Thessaloniki, Greece, 56429 Russian Federation GSK Investigational Site Irkutsk, Russian Federation, 664079 GSK Investigational Site Moscow, Russian Federation, 125367 GSK Investigational Site Rostov-on-Don, Russian Federation, 344022 GSK Investigational Site Smolensk, Russian Federation, 214018 GSK Investigational Site St'Petersburg, Russian Federation, 194354 Spain GSK Investigational Site Alicante, Spain, 03010 GSK Investigational Site Elche (Alicante), Spain, 03203 GSK Investigational Site Getafe/Madrid, Spain, 28905 GSK Investigational Site Granada, Spain, 18003 GSK Investigational Site Madrid, Spain, 28040 GSK Investigational Site Murcia, Spain GSK Investigational Site Pama de Mallorca, Spain, 07010 收起 <<
NCT01381549 - Terminated(Microbiological fin... 展开 >>dings of resistance on therapy in patients with complicated urinary tract infection) 收起 << - -

Imipenem monohydrate 参考文献

[1]Tuan Anh N, Nga TV, et al. Molecular epidemiology and antimicrobial resistance phenotypes of Acinetobacter baumannii isolated from patients in three hospitals in southern Vietnam. J Med Microbiol. 2017 Jan;66(1):46-53.

[2]Ly NS, Bulitta JB, et al. Colistin and doripenem combinations against Pseudomonas aeruginosa: profiling the time course of synergistic killing and prevention of resistance. J Antimicrob Chemother. 2015 May;70(5):1434-42.

[3]Hellinger WC, Brewer NS. Imipenem. Mayo Clin Proc. 1991;66(10):1074–1081

[4]Zhu W, Wang Y, Cao W, Cao S, Zhang J. in vitro evaluation of antimicrobial combinations against imipenem-resistant Acinetobacter baumannii of different MICs. J Infect Public Health. 2018;11(6):856–860

[5]Balfour JA, Bryson HM, Brogden RN. Imipenem/cilastatin: an update of its antibacterial activity, pharmacokinetics and therapeutic efficacy in the treatment of serious infections. Drugs. 1996;51(1):99–136

Imipenem monohydrate 实验方案

计算器
存储液制备 1mg 5mg 10mg

1 mM

5 mM

10 mM

3.15mL

0.63mL

0.32mL

15.75mL

3.15mL

1.58mL

31.51mL

6.30mL

3.15mL

Imipenem monohydrate 技术信息

CAS号74431-23-5
分子式C12H19N3O5S
分子量 317.361
别名 亚胺培南一水物 ;N-Formimidoyl thienamycin monohydrate;MK0787 monohydrate;N-Formimidoyl Thienamycin;Imipenem (hydrate);Imipenem
运输蓝冰
存储条件

液体 -20°C:3-6个月-80°C:12个月

粉末 Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
溶解度

H2O: 6 mg/mL(18.91 mM)，配合低频超声，并水浴加热至45℃助溶
动物实验配方

Tags: Imipenem | 74431-23-5 | N-Formimidoyl thienamycin | MK0787 | MK 0787 | MK-0787 | Anti-infection | Bacterial | Antibiotic | 仅供科研使用 | AmBeed-信号通路专用抑制剂 | Imipenem monohydrate 纯度/质量文件 | Imipenem monohydrate 生物活性 | Imipenem monohydrate 临床数据 | Imipenem monohydrate 参考文献 | Imipenem monohydrate 实验方案 | Imipenem monohydrate 技术信息

Ambeed 相关网站 Ambeed.cn Ambeed.com
Ambeed
关于我们
联系我们
资讯中心
网站地图
产品手册
  • 批次文件查询
    • 客户支持
    技术支持
    专业术语
    缩略词释义
    质量手册
    产品咨询
    计算器
    活动政策
    订购方法
    积分商城
    活动声明
    联系我们
    400-920-2911 sales@ambeed.cn tech@ambeed.cn
    Ambeed 只为有资质的科研机构、医药企业基于科学研究或药证申报的用途提供医药研发服务，不为任何个人或者非科研性质用途提供服务。

    尊敬的 Ambeed 客户您好，
    请您选择所在区域，我们将转接对应客服为您服务！

    热门区域

    A

    B

    C

    F

    G

    H

    J

    L

    N

    Q

    S

    T

    X

    Y

    Z

    热 A B C F G H J L N Q S T X Y Z