5-HTP | 5-Hydroxy-L-tryptophan | Endogenous Metabolite | AmBeed-信号通路专用抑制剂

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5-羟基色氨酸 /H-Trp(5-OH)-OH {[allProObj[0].p_purity_real_show]}

货号：A102374 同义名： 5-Hydroxy-L-tryptophan;L-5-HTP

H-Trp(5-OH)-OH是神经递质血清素的前体，用于研究抑郁症、偏头痛和纤维肌痛症。

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There will be a HazMat fee per item when shipping a dangerous goods. The HazMat fee will be charged to your UPS/DHL/FedEx collect account or added to the invoice unless the package is shipped via Ground service. Ship by air in Excepted Quantity (each bottle), which is up to 1g/1mL for class 6.1 packing group I or II, and up to 25g/25ml for all other HazMat items.

Type	HazMat fee for 500 gram (Estimated)
Excepted Quantity	USD 0.00
Limited Quantity	USD 15-60
Inaccessible (Haz class 6.1), Domestic	USD 80+
Inaccessible (Haz class 6.1), International	USD 150+
Accessible (Haz class 3, 4, 5 or 8), Domestic	USD 100+
Accessible (Haz class 3, 4, 5 or 8), International	USD 200+

H-Trp(5-OH)-OH 化学结构
CAS号：4350-09-8

H-Trp(5-OH)-OH 3D分子结构
CAS号：4350-09-8

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H-Trp(5-OH)-OH 纯度/质量文件产品仅供科研

货号：A102374 标准纯度： {[allProObj[0].p_purity_real_show]} 产品说明书

批次查询：批次纯度: COA SDS NMR HPLC CNMR LC-MS

全球学术期刊中引用的产品: • JMC, 2024. Ambeed. [ A919389 , A918471 , A995972 ]; • Anal. Chem., 2024, 96(50): 19947-19954. Ambeed. [ A261947 , A1165388 ]; • ACS Biomater. Sci. Eng., 2024. Ambeed. [ A220462 ]; • ACS Biomater. Sci. Eng., 2024. Ambeed. [ A165235 , A110205 ]; • Pharmaceutics, 2024, 16(12): 1546. Ambeed. [ A272538 , A187261 , A691302 , A506702 ]; 更多 >

H-Trp(5-OH)-OH 生物活性

描述

L-5-Hydroxytryptophan (L-5-HTP) is a naturally occurring amino acid and dietary supplement that serves multiple roles including as an antidepressant, appetite suppressant, and sleep aid. It is the direct precursor to the neurotransmitter serotonin and acts as a reserpine antagonist^[1]. L-5-HTP is also employed in the treatment of various conditions such as fibromyalgia, myoclonus, migraine, and cerebellar ataxia^[2].^[3].^[4].^[5].

H-Trp(5-OH)-OH 参考文献

[1]ARVID CARLSSON, et al. 3,4-Dihydroxyphenylalanine and 5-Hydroxytryptophan as Reserpine Antagonists. Nature 180, page1200 (1957).

[2]Caruso I, et al. Double-blind study of 5-hydroxytryptophan versus placebo in the treatment of primary fibromyalgia syndrome. J Int Med Res. 1990 May-Jun;18(3):201-9.

[3]Thal LJ, et al. Treatment of myoclonus with L-5-hydroxytryptophan and carbidopa: clinical, electrophysiological, and biochemical observations. Ann Neurol. 1980 Jun;7(6):570-6.

[4]Boiardi A, et al. 5-OH-Tryptophane in migraine: clinical and neurophysiological considerations. J Neurol. 1981;225(1):41-6.

[5]Trouillas P, et al. Improvement of cerebellar ataxia with levorotatory form of 5-hydroxytryptophan. A double-blind study with quantified data processing. Arch Neurol. 1988 Nov;45(11):1217-22.

H-Trp(5-OH)-OH 实验方案

计算器

存储液制备

1mg

5mg

10mg

1 mM

5 mM

10 mM

4.54mL

0.91mL

0.45mL

22.70mL

4.54mL

2.27mL

45.41mL

9.08mL

4.54mL

H-Trp(5-OH)-OH 技术信息

CAS号	4350-09-8
分子式	C₁₁H₁₂N₂O₃
分子量	220.225

别名	5-Hydroxy-L-tryptophan;L-5-HTP;Oxitriptan, 5 Hydroxytryptophan, 5-hydroxy-L-tryptophan, 5-HTP, Oxytryptophan;L-oxitriptan;Oxitriptan;L-5-Hydroxytryptophan
运输	蓝冰

存储条件

In solvent -20°C:3-6个月-80°C:12个月

Pure form Keep in dark place,Inert atmosphere,Room temperature

溶解度

DMSO: 12 mg/mL(54.49 mM)，配合低频超声，并水浴加热至45℃助溶，注意：DMSO长时间开封后，会吸水并导致溶解能力下降，请避免使用长期开封的DMSO

动物实验配方

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5-羟基色氨酸 /H-Trp(5-OH)-OH {[allProObj[0].p_purity_real_show]}

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H-Trp(5-OH)-OH 技术信息

最近浏览的产品

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