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描述 | Gentamicin is an aminoglycoside bactericidal antibiotic, which is mainly aimed at gram-negative bacterial infection. Gentamicin can also establish an animal model of experimental renal failure by inducing nephrotoxicity. |
体内研究 | Gentamicin (oral and injectable forms) showed effective antibacterial activity against Yersinia pestis in a mouse infection model [2] . Gentamicin (0.27 g/kg) significantly reduced the number of bacteria on foreign bodies in mice [3] . |
体外研究 | Gentamicin is a more potent in vitro bacterial inhibitor than the penicillin-streptomycin combination, is non-toxic to tissue culture monolayers and does not inhibit viral replication [1] . Gentamicin is bactericidal against a wider range of organisms (Pseudomonas aeruginosa, Proteus mirabilis and Streptococcus faecalis) than penicillin and streptomycin [1] . |
CAS号 | 1403-66-3 |
SMILES Code | NONE |
MDL No. | MFCD00072030 |
别名 | |
运输 | 蓝冰 |
存储条件 |
In solvent -20°C:3-6个月-80°C:12个月 Pure form Keep in dark place, inert atmosphere, 2-8°C |
溶解方案 |
H2O: 100 mg/mL,配合低频超声助溶 |