货号:A213166 同义名: SQ28555;Fosinopril (sodium salt)
Fosinopril (sodium) 是一种血管紧张素转换酶(ACE)抑制剂的原药,可用于高血压和慢性心力衰竭的治疗。
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描述 | Fosinopril sodium is the ester prodrug of an angiotensin-converting enzyme (ACE) inhibitor and has the greatest lipophilicity[3]. Once daily administration of fosinopril at 20 and 40 mg was safe and well tolerated, provided a sustained beneficial hemodynamic effect, improved left ventricular performance, and reduced symptoms of dyspnea, resulting in a reduced need for supplemental diuretic therapy[4]. Further, Fosinopril ameliorated diabetic renal injuries by inhibiting oxidative stress[5]. |
计算器 | ||||
存储液制备 | 1mg | 5mg | 10mg | |
1 mM 5 mM 10 mM |
1.71mL 0.34mL 0.17mL |
8.54mL 1.71mL 0.85mL |
17.08mL 3.42mL 1.71mL |
CAS号 | 88889-14-9 |
分子式 | C30H45NNaO7P |
分子量 | 585.644 |
别名 | SQ28555;Fosinopril (sodium salt);Squibb Brand of Fosinopril Sodium;Sodium, Fosinopril;Tensocardil;Tenso Stop;Fosinil;Dynacil;Staril;Monopril |
运输 | 蓝冰 |
存储条件 |
液体 -20°C:3-6个月-80°C:12个月 粉末 Inert atmosphere,Store in freezer, under -20°C |
溶解度 |
DMSO: 1 mg/mL(1.71 mM),配合低频超声助溶,注意:DMSO长时间开封后,会吸水并导致溶解能力下降,请避免使用长期开封的DMSO H2O: 25 mg/mL(42.69 mM),配合低频超声,并水浴加热至45℃助溶 无水乙醇: 15 mg/mL(25.61 mM),配合低频超声助溶,注意:无水乙醇开封后,易挥发,也会吸收空气中的水分,导致溶解能力下降,请避免使用开封较久的乙醇 |
动物实验配方 |