货号:A127543 同义名: BAY Vp 2674;PD160788
Enrofloxacin is a fluoroquinolone antibiotic used as a veterinary antibacterial agent.
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描述 | Enrofloxacin (EF) is an extensively used animal-specific antibacterial agent that leaves drug residues in the environment[3]. The in vivo effectiveness of enrofloxacin against E. coli in different organs varied, with the Emax ranging from - 4.4 to - 5.8 Log10 colony forming units (cfu)/mL or cfu/g. The AUC0-24/MIC ratio of the combination of enrofloxacin and ciprofloxacin producing bactericidal and elimination effects were 21.29 and 32.13 in blood; 41.68, and 58.52 in the liver; and 27.65 and 46.22 in the lung, respectively[4]. The most effective antibiotics tested in vitro were fluoroquinolones (MIC90 danofloxacin 0.312 μg/mL, enrofloxacin 0.312 μg/mL, marbofloxacin 0.625 μg/mL)[5]. Enrofloxacin reduced C. jejuni cell densities within the cecal and colonic digesta for all treatments, and densities shed in feces as a function of antibiotic duration[6]. |
NCT号 | 适应症或疾病 | 临床期 | 招募状态 | 预计完成时间 | 地点 |
NCT03575312 | Healthy | Not Applicable | Completed | - | Germany ... 展开 >> Fraunhofer Institute for Toxicology and Experimental Medicine Hannover, Germany, 30625 收起 << |
计算器 | ||||
存储液制备 | 1mg | 5mg | 10mg | |
1 mM 5 mM 10 mM |
2.78mL 0.56mL 0.28mL |
13.91mL 2.78mL 1.39mL |
27.82mL 5.56mL 2.78mL |
CAS号 | 93106-60-6 |
分子式 | C19H22FN3O3 |
分子量 | 359.395 |
别名 | BAY Vp 2674;PD160788;endrofloxicin.;CFPQ;Enrofloxacine;Baytril;ENR |
运输 | 蓝冰 |
存储条件 |
液体 -20°C:3-6个月-80°C:12个月 粉末 Inert atmosphere,Room Temperature |
溶解度 |
DMSO: 9 mg/mL(25.04 mM),配合低频超声助溶,注意:DMSO长时间开封后,会吸水并导致溶解能力下降,请避免使用长期开封的DMSO H2O: 1 mg/mL(2.78 mM),配合低频超声,并水浴加热至45℃助溶 |
动物实验配方 |