Edrophonium chloride is an acetylcholinesterase inhibitor with a rapid onset (approximately 30 seconds) and short duration (approximately 5 minutes). The edrophonium challenge test may be useful for diagnosing cervical dystonia[3]. After low doses of edrophonium (1.0 mumol/kg) there was a significant correlation between the monophasic potentiation of twitch tension and the plasma concentration of the drug[4]. Moreover, electrophysiological effects of edrophonium in man are mediated primarily through autonomic innervation of the heart[5].
United States, New York
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James J Peters VA Medical Center
Recruiting
Bronx, New York, United States, 10468
Contact: Jill M Wecht, Ed.D 718-584-9000 ext 3122 jm.wecht@va.gov
Contact: Matthew T Maher, MS 7185849000 ext 1706 matthew.maher@va.gov
Principal Investigator: Jill M Wecht, Ed.D.
Sub-Investigator: Gregory Schilero, M.D.
Sub-Investigator: Miroslav Radulovic, M.D.
Sub-Investigator: William A Bauman, M.D. 收起 <<
United States, New York
... 展开 >>
James J Peters VA Medical Center
Recruiting
Bronx, New York, United States, 10468
Contact: Jill M Wecht, Ed.D 718-584-9000 ext 3122 jm.wecht@va.gov
Contact: Matthew T Maher, MS 7185849000 ext 1706 matthew.maher@va.gov
Principal Investigator: Jill M Wecht, Ed.D.
Sub-Investigator: Gregory Schilero, M.D.
Sub-Investigator: Miroslav Radulovic, M.D.
Sub-Investigator: William A Bauman, M.D. 收起 <<
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