货号:A342537
同义名:
丹磺胺
/ Monodansyl cadaverine; MDC
Dansylcadaverine is a fluorescent probe labled with thymosin β4.
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描述 | Dansylcadaverine is a fluorescent probe labled with thymosin β4[1]. Dansylcadaverine inhibits EGF internalization by preventing it from clustering in clathrin-coated pits[2]. Immunofluorescent localization of dansylcadaverine in dansylcadaverine-treated cells demonstrates incorporation of the amino into endocytic vesicles. Covalent coupling of dansylcadaverine to cellular membranes may account for its ability to interfere with endocytosis in certain susceptible cells[3]. Dansylcadaverine is 20-fold more potent than amantadine in blocking virus and alpha 2-macroglobulin uptake[4]. Dansylcadaverine, which structurally resembles the calmodulin antagonists W-7 and W-5, prevented the calmodulin dependent stimulation of 3':5'-cyclic nucleotide phosphodiesterase in vitro[5]. |
计算器 | ||||
存储液制备 | ![]() |
1mg | 5mg | 10mg |
1 mM 5 mM 10 mM |
2.98mL 0.60mL 0.30mL |
14.90mL 2.98mL 1.49mL |
29.81mL 5.96mL 2.98mL |
CAS号 | 10121-91-2 |
分子式 | C17H25N3O2S |
分子量 | 335.46 |
SMILES Code | O=S(C1=C2C=CC=C(N(C)C)C2=CC=C1)(NCCCCCN)=O |
MDL No. | MFCD00042704 |
别名 | 丹磺胺 ;Monodansyl cadaverine; MDC |
运输 | 蓝冰 |
InChI Key | MLEBFEHOJICQQS-UHFFFAOYSA-N |
Pubchem ID | 4247 |
存储条件 |
In solvent -20°C:3-6个月-80°C:12个月 Pure form Keep in dark place, inert atmosphere, store in freezer, under -20°C |
溶解方案 |
DMSO: 60 mg/mL(178.86 mM),配合低频超声助溶,注意:DMSO长时间开封后,会吸水并导致溶解能力下降,请避免使用长期开封的DMSO |