D-Sorbitol (Sorbitol) is a six-carbon sugar alcohol and can used as a stabilizing excipient and/or isotonicity agent, sweetener, humectant, thickener and dietary supplement. In oral liquids, D-Sorbitol (Sorbitol) is used as a sugar substitute and as a drug stabilizer. D-Sorbitol (Sorbitol) is also used as a solubility enhancer for drugs such as indomethacin. D-Sorbitol (Sorbitol) is commonly used as a stabilizing excipient and/or isotonicity agent in both liquid and lyophilized parenteral protein formulations. D-Sorbitol (Sorbitol) is used in topical formulations as a humectant[2]. D-Sorbitol acts as a competitive inhibitor with a Ki of 5.5 mM against D-glucose, D-xylose, and D-ribose[3]. The hepatic clearance of D-sorbitol was proven to be a reliable parameter for evaluating the functional liver plasma flow[4]. In normal and under septic conditions, hepatic clearance of D-sorbitol either by bolus or a SS (steady-state) infusion is comparable[5].
Germany
... 展开 >> University Hospital Regensburg, Department of Pediatric Hematology and Oncology
Recruiting
Regensburg, Germany, 93053
Contact: Selim Corbacioglu, MD +49(0)941 944-2101 selim.corbacioglu@ukr.de
Principal Investigator: Selim Corbacioglu, MD 收起 <<
United States, California
... 展开 >>
University of California - San Francisco
San Francisco, California, United States, 94158-2549
Stanford University
Stanford, California, United States, 94305
United States, Colorado
Barbara Davis Center
Aurora, Colorado, United States, 80045
United States, Connecticut
Yale University
New Haven, Connecticut, United States, 06519
United States, Florida
University of Florida
Gainesville, Florida, United States, 32610
University of Miami
Miami, Florida, United States, 33136
University of South Florida Diabetes Center
Tampa, Florida, United States, 33612
United States, Indiana
Indiana University-Riley Hospital for Children
Indianapolis, Indiana, United States, 46202
United States, Minnesota
University of Minnesota
Minneapolis, Minnesota, United States, 55455
United States, New York
Columbia University-Naomi Berrie Diabetes Center
New York, New York, United States, 10032
United States, Pennsylvania
University of Pittsburgh
Pittsburgh, Pennsylvania, United States, 15224
United States, Tennessee
Vanderbilt Eskind Diabetes Clinic
Nashville, Tennessee, United States, 37232
United States, Washington
Benaroya Research Institute
Seattle, Washington, United States, 98101 收起 <<
Castration Resistant Metastati... 展开 >>c Prostate Cancer 收起 <<
Phase 2
Active, not recruiting
December 2019
United States, District of Col... 展开 >>umbia
Sibley Memorial Hospital
Washington, District of Columbia, United States, 20016
United States, Maryland
SKCCC at Johns Hopkins
Baltimore, Maryland, United States, 21205 收起 <<
United Kingdom
... 展开 >> GSK Investigational Site
Cambridge, United Kingdom, CB2 2GG
GSK Investigational Site
Cardiff, United Kingdom, CF144XW
GSK Investigational Site
London, United Kingdom, EC1M 6BQ 收起 <<
United States, California
... 展开 >>
Kaiser Permanente Vaccine Study Center
Oakland, California, United States, 94612-3610
Children's Hospital & Research Center Oakland - Primary Care Clinic
Oakland, California, United States, 94618-1033
United States, Georgia
Emory Children's Center - Pediatric Infectious Diseases
Atlanta, Georgia, United States, 30322-1014
United States, Iowa
University of Iowa - Vaccine Research & Education Unit
Iowa City, Iowa, United States, 52242-2600
United States, Maryland
University of Maryland School of Medicine - Center for Vaccine Development - Baltimore
Baltimore, Maryland, United States, 21201-1509
United States, Missouri
Children's Mercy Hospital and Clinics - Infectious Diseases
Kansas City, Missouri, United States, 64108-4619
United States, North Carolina
Duke Translational Medicine Institute - Clinical Vaccine Unit
Durham, North Carolina, United States, 27704-2120
United States, Pennsylvania
Primary Physicians Research Inc. - Pittsburgh
Pittsburgh, Pennsylvania, United States, 15241-3100
United States, Tennessee
Vanderbilt University - Pediatric - Vanderbilt Vaccine Research Center
Nashville, Tennessee, United States, 37232-2573
United States, Texas
The University of Texas Medical Branch - Sealy Center for Vaccine Development (SCVD)
Galveston, Texas, United States, 77555-1121
Baylor College of Medicine - Molecular Virology and Microbiology
Houston, Texas, United States, 77030-3411
United States, Washington
Group Health Research Institute - Seattle
Seattle, Washington, United States, 98101-1466
Seattle Children's Hospital - Infectious Diseases
Seattle, Washington, United States, 98105-3901 收起 <<
United States, Washington
... 展开 >>
Washington State University, College of Pharmacy, Department of Pharmacotherapy
Spokane, Washington, United States, 99210-1495 收起 <<
Taiwan
... 展开 >> Kaohsiung Chang Gung Memorial Hospital
Kaohsiung, Taiwan, 83301
Keelung Chang Gung Memorial Hospital
Keelung, Taiwan, 20401
Far Eastern Memorial Hospital
New Taipei City, Taiwan, 22056
Buddhist TzuChi General Hospital, Taipei Branch
New Taipei City, Taiwan, 23142
China Medical University Hospital
Taichung, Taiwan, 40447
Shin Kong Wu Ho-Su Memorial Hospital
Taipei, Taiwan, 11168 收起 <<
United States, Alabama
... 展开 >>
Birmingham, Alabama, United States
United States, California
Los Angeles, California, United States
United States, Illinois
Chicago, Illinois, United States
United States, New York
Lake Success, New York, United States
United States, Ohio
Columbus, Ohio, United States
United States, Pennsylvania
Duncansville, Pennsylvania, United States
United States, Tennessee
Chattanooga, Tennessee, United States
United States, Texas
Carrollton, Texas, United States
Belgium
Brussels, Belgium
Leuven, Belgium
Roeselare, Belgium
Mexico
Guadalajara, Jalisco, Mexico
Guadalajara, Mexico
Mexico, Mexico
México, Mexico
Querétaro, Mexico
Netherlands
Rotterdam, Netherlands
Poland
Gdansk, Poland
Warszawa, Poland
Wroclaw, Poland
Thailand
Bangkok, Thailand
Chiang Mai, Thailand 收起 <<
Sweden
... 展开 >> Danderyd Hospital
Recruiting
Stockholm, Sweden
Karolinska University Hospital
Recruiting
Stockholm, Sweden
Stockholm South General Hospital
Recruiting
Stockholm, Sweden 收起 <<
Israel
... 展开 >> Hadassah Hebrew University Medical Center, Department of Anesthesiology
Jerusalem, Israel, 91120
Hadassah En Kerem Medical Centre
Jerusalem, Israel 收起 <<
China, Guangdong
... 展开 >>
Southern Medical University - Nanfang Hospital
Guangzhou, Guangdong, China
The First Affiliated Hospital, Sun Yat-sen University
Guangzhou, Guangdong, China
The Second Affiliated Hospital, Sun Yat-sen University
Guangzhou, Guangdong, China
China, Hubei
Zhongnan Hospital of Wuhan University
Wuhan, Hubei, China
China, Jiangsu
Nanjing First Hospital
Nanjing, Jiangsu, China
The First Affiliated Hospital with Nanjing Medical University
Nanjing, Jiangsu, China
China, Shanghai
Shanghai Changhai Hospital
Shanghai, Shanghai, China
Shanghai Jiaotong University Medical School - Renji Hospital
Shanghai, Shanghai, China
Shanghai Jiaotong University Medical School - Ruijin Hospital
Shanghai, Shanghai, China 收起 <<
搜索
