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头孢他啶 /Ceftazidime {[allProObj[0].p_purity_real_show]}

货号:A516848 同义名: GR20263

Ceftazidime is a semisynthetic, broad-spectrum, third-generation cephalosporin β-lactam antibiotic used for the treatment of a number of bacterial infections.

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There will be a HazMat fee per item when shipping a dangerous goods. The HazMat fee will be charged to your UPS/DHL/FedEx collect account or added to the invoice unless the package is shipped via Ground service. Ship by air in Excepted Quantity (each bottle), which is up to 1g/1mL for class 6.1 packing group I or II, and up to 25g/25ml for all other HazMat items.

Type HazMat fee for 500 gram (Estimated)
Excepted Quantity USD 0.00
Limited Quantity USD 15-60
Inaccessible (Haz class 6.1), Domestic USD 80+
Inaccessible (Haz class 6.1), International USD 150+
Accessible (Haz class 3, 4, 5 or 8), Domestic USD 100+
Accessible (Haz class 3, 4, 5 or 8), International USD 200+
Ceftazidime 化学结构 CAS号:72558-82-8
Ceftazidime 化学结构
CAS号:72558-82-8
Ceftazidime 3D分子结构
CAS号:72558-82-8
Ceftazidime 化学结构 CAS号:72558-82-8
Ceftazidime 3D分子结构 CAS号:72558-82-8
规格 价格 会员价 库存 数量
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Ceftazidime 纯度/质量文件 产品仅供科研

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Ceftazidime 生物活性

描述 Ceftazidime (GR20263) is an antibiotic with broad-spectrum activity against both Gram-positive and Gram-negative aerobic bacteria. It shows effectiveness against Enterobacteriaceae, including β-lactamase-positive strains, and is resistant to hydrolysis by most β-lactamases[1].
体内研究

A regimen of ceftazidime involving a 2-hour infusion of 2000 mg, administered every 8 hours for 24 hours, moderately reduces bacterial density in a murine thigh infection model[4].

体外研究

Ceftazidime (0-8 μg/mL, over 24 hours) exhibits both antibacterial and anti-biofilm properties against P. aeruginosa strains[2].

Ceftazidime (0-40 μg/mL, for 18-20 hours) demonstrates inhibitory effects on S. maltophilia isolates[3].

Ceftazidime 参考文献

[1]Richards DM, et al. Ceftazidime. A review of its antibacterial activity, pharmacokinetic properties and therapeutic use. Drugs. 1985 Feb;29(2):105-61.

[2]Esmat Kamali, et al. In vitro activities of cellulase and ceftazidime, alone and in combination against Pseudomonas aeruginosa biofilms. BMC Microbiol. 2021 Dec 16;21(1):347.

[3]Qiuxia Lin, et al. Avibactam potentiated the activity of both ceftazidime and aztreonam against S. maltophilia clinical isolates in vitro. BMC Microbiol. 2021 Feb 22;21(1):60.

[4]Shawn H MacVane, et al. Unexpected in vivo activity of ceftazidime alone and in combination with avibactam against New Delhi metallo-β-lactamase-producing Enterobacteriaceae in a murine thigh infection model. Antimicrob Agents Chemother. 2014 Nov;58(11):7007-9.

Ceftazidime 实验方案

计算器
存储液制备 1mg 5mg 10mg

1 mM

5 mM

10 mM

1.83mL

0.37mL

0.18mL

9.15mL

1.83mL

0.91mL

18.30mL

3.66mL

1.83mL

Ceftazidime 技术信息

CAS号72558-82-8
分子式C22H22N6O7S2
分子量 546.576
别名 GR20263
运输蓝冰
存储条件

液体 -20°C:3-6个月-80°C:12个月

粉末 Keep in dark place,Inert atmosphere,Room temperature

溶解度

H2O: 100 mg/mL(182.96 mM),配合低频超声助溶

动物实验配方
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