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头孢妥仑匹酯 /Cefditoren pivoxil {[allProObj[0].p_purity_real_show]}

货号:A212367 同义名: Cefditoren (Pivoxil);Cefditoren pivoxyl

Cefditoren Pivoxil is a third-generation oral cephalosporin with a broad spectrum of activity against pathogens, including both Gram-positive and -negative bacteria, and is stable to hydrolysis by many common β-lactamases.

Cefditoren pivoxil 化学结构 CAS号:117467-28-4
Cefditoren pivoxil 化学结构
CAS号:117467-28-4
Cefditoren pivoxil 3D分子结构
CAS号:117467-28-4
Cefditoren pivoxil 化学结构 CAS号:117467-28-4
Cefditoren pivoxil 3D分子结构 CAS号:117467-28-4
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Cefditoren pivoxil 纯度/质量文件 产品仅供科研

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Cefditoren pivoxil 生物活性

描述 Cefditoren Pivoxil (ME 1207) is classified as a third-generation, broad-spectrum oral cephalosporin antibiotic that exhibits enhanced resistance to many common β-lactamases. It demonstrates activity against both Gram-negative and Gram-positive organisms, making it applicable in the study and treatment of infectious diseases like acute exacerbations of chronic bronchitis, community-acquired pneumonia (CAP), streptococcal pharyngitis/tonsillitis, and uncomplicated skin and skin structure infections[1].[2].
体外研究

Cefditoren Pivoxil shows potent activity against a range of pathogens, including Streptococcus pneumoniae, Streptococcus pyogenes, Staphylococcus aureus, Haemophilus influenzae, Haemophilus parainfluenzae, and Moraxella catarrhalis[1].

Cefditoren pivoxil 临床研究

NCT号 适应症或疾病 临床期 招募状态 预计完成时间 地点
NCT00598403 Urinary Tract Infections Phase 3 Completed - Greece ... 展开 >> General Hospital of Chest Disease of Athens Athens, Greece General Hospital of Thessaloniki Thessaloniki, Greece Spain CS Rincón de Loix Benidorm, Alicante, Spain, 03500 CAP Cornella Cornella de Llobregat, Barcelona, Spain, 08940 CAP 17 setembre El Prat de Llobregat, Barcelona, Spain, 08820 CAP Bartomeu Fabres Anglada Gava, Barcelona, Spain, 08850 CAP Amadeu Torner Hospitalet de Llobregat, Barcelona, Spain, 08902 CAP Florida Nord Hospitalet de Llobregat, Barcelona, Spain, 08905 CAP Dr. Vicens Papaceit La Roca del Valles, Barcelona, Spain, 08430 CAP Les Bases-Manresa 3 Manresa, Barcelona, Spain, 08243 CAP La Riera Mataro, Barcelona, Spain, 08302 CAP El Maresme Mataro, Barcelona, Spain, 08303 CAP Navas-Balsareny Navas, Barcelona, Spain, 08670 CAP Remei Vic, Barcelona, Spain, 08500 CS San Telmo Jerez de la frontera, Cadiz, Spain, 11408 CS Cabra Cabra, Cordoba, Spain, 14940 CS Lucena Lucena, Cordoba, Spain, 14900 CS Rute Rute, Cordoba, Spain, 14960 CS Billabona Billabona, Guipuzcoa, Spain, 20150 CS Legazpi Legazpi, Guipuzcoa, Spain, 20230 CS Monzón Urbano Monzon, Huesca, Spain, 22400 CS Basurto Bilbao, Vizcaya, Spain, 48013 CS Cabo Huertas Alicante, Spain, 03540 CAP El Clot Barcelona, Spain, 08018 Fundacion Puigvert Barcelona, Spain, 08025 CS Sagasta Ruiseñores Zaragoza, Spain, 50006 CS Torrero La Paz Zaragoza, Spain, 50007 CS Torre Ramona Zaragoza, Spain, 50013 CS Arrabal Zaragoza, Spain, 50015 CS Bombarda Zaragoza, Spain, 50017 收起 <<
NCT01553006 Rhinosinusitis Phase 4 Unknown September 2012 Thailand ... 展开 >> Thammasat University Recruiting Prathumthani, Thailand, 12120 Contact: Orapan Poachanukoon, MD.    66819316781    orapanpoachanukoon@yahoo.com 收起 <<

Cefditoren pivoxil 参考文献

[1]Wellington K, et al. Cefditoren pivoxil: a review of its use in the treatment of bacterial infections. Drugs. 2004;64(22):2597-618.

[2]Cafini F, et al. Enhanced in vivo activity of cefditoren in pre-immunized mice against penicillin-resistant S. pneumoniae (serotypes 6B, 19F and 23F) in a sepsis model. PLoS One. 2010 Aug 10;5(8):e12041.

Cefditoren pivoxil 实验方案

计算器
存储液制备 1mg 5mg 10mg

1 mM

5 mM

10 mM

1.61mL

0.32mL

0.16mL

8.06mL

1.61mL

0.81mL

16.11mL

3.22mL

1.61mL

Cefditoren pivoxil 技术信息

CAS号117467-28-4
分子式C25H28N6O7S3
分子量 620.721
别名 Cefditoren (Pivoxil);Cefditoren pivoxyl;ME 1207;Cefditoren pivaloyloxymethyl ester
运输蓝冰
存储条件

液体 -20°C:3-6个月-80°C:12个月

粉末 Keep in dark place,Inert atmosphere,Store in freezer, under -20°C

溶解度

DMSO: 105 mg/mL(169.16 mM),注意:DMSO长时间开封后,会吸水并导致溶解能力下降,请避免使用长期开封的DMSO

动物实验配方
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