比阿培南 /Biapenem
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货号：A699164
同义名：
CLI 86815;L 627
Biapenem 属于五环三萜类化合物，具有抗菌活性，能够对耐甲氧西林和敏感甲氧西林金黄色葡萄球菌的参考菌株产生抗菌效果。
Biapenem 化学结构
Biapenem 3D分子结构
规格
价格
会员价
库存
数量
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Biapenem 纯度/质量文件 产品仅供科研
货号：A699164
标准纯度：
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Biapenem 质控信息
Biapenem 生物活性
描述
Biapenem is a new parenteral carbapenem antibacterial agent with a broad spectrum of in vitro antibacterial activity encompassing many Gram-negative and Gram-positive aerobic and anaerobic bacteria, including species producing beta-lactamases[3] [4] [3] [5]
Biapenem 临床研究
NCT号
适应症或疾病
临床期
招募状态
预计完成时间
地点
NCT01702649
Healthy Volunteers
... 展开 >> Bacterial Infections 收起 <<
Phase 1
Completed
-
United States, Arizona
... 展开 >>
Celerion
Tempe, Arizona, United States, 85283 收起 <<
NCT01772836
Healthy Volunteers
... 展开 >> Bacterial Infections 收起 <<
Phase 1
Completed
-
Australia, South Australia
... 展开 >>
CMAX
Adelaide, South Australia, Australia, 5000 收起 <<
NCT01751269
Healthy Volunteers
... 展开 >> Bacterial Infections 收起 <<
Phase 1
Completed
-
Australia, South Australia
... 展开 >>
CMAX
Adelaide, South Australia, Australia, 5000 收起 <<
Biapenem 参考文献
[1] Perry CM, Ibbotson T. Biapenem. Drugs. 2002;62(15):2221-34; discussion 2235.
[2] Aldridge KE, Morice N, Schiro DD. In vitro activity of biapenem (L-627), a new carbapenem, against anaerobes. Antimicrob Agents Chemother. 1994 Apr;38(4):889-93.
[3] Perry CM, Ibbotson T. Biapenem. Drugs. 2002;62(15):2221-34; discussion 2235.
[4] Gatti DL. Biapenem inactivation by B2 metallo β-lactamases: energy landscape of the post-hydrolysis reactions. PLoS One. 2012;7(1):e30079.
[5] Kasahara S, Hara T, Tsurumi H, Goto N, Kanemura N, Yoshikawa T, Yamada T, Sawada M, Takahashi T, Moriwaki H. [Clinical effects of biapenem on febrile neutropenia in patients with hematological malignancy]. Jpn J Antibiot. 2008 Jun;61(3):115-21.
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Biapenem 实验方案
计算器
摩尔计算器
总药量计算器
工作液计算器
存储液制备
1mg
5mg
10mg
1 mM
5 mM
10 mM
2.85mL
0.57mL
0.29mL
14.27mL
2.85mL
1.43mL
28.54mL
5.71mL
2.85mL
Biapenem 技术信息
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