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烯丙基雌烯醇 /Allylestrenol {[allProObj[0].p_purity_real_show]}

货号:A810685 同义名: 烯丙雌醇

Allylestrenol is a synthetic steroidal progestin that is used to prevent recurrent pregnancy loss, threatened miscarriage, and premature labor.

Allylestrenol 化学结构 CAS号:432-60-0
Allylestrenol 化学结构
CAS号:432-60-0
Allylestrenol 3D分子结构
CAS号:432-60-0
Allylestrenol 化学结构 CAS号:432-60-0
Allylestrenol 3D分子结构 CAS号:432-60-0
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Allylestrenol 纯度/质量文件 产品仅供科研

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Allylestrenol 生物活性

描述 Allylestrenol is a synthetic steroidal progestin that is used to prevent recurrent pregnancy loss, threatened miscarriage, and premature labor. Allylestrenol combined with ritodrine can significantly reduce the expression levels of IL-17, IL-10 and IL-6 in TPTL (threatened premature labor), reduce adverse pregnancy conditions, prolong gestational weeks, and has higher safety and better application value[3]. Allylestrenol is useful for treatment of urinary disturbances caused by prostatic hypertrophy[4]. Allylestrenol is an effective and safe medical treatment for patients with symptomatic BPH(benign prostatic hypertrophy). Hormonal and histopathologic findings suggest that the prostate gland may regrow after discontinuation of medication[5].

Allylestrenol 参考文献

[1]Saure A, Karjalainen O, et al. The effect of synthetic gestagens on progesterone formation in vitro in human corpus luteum of early pregnancy. Eur J Obstet Gynecol Reprod Biol. 1976;6(4):223-34.

[2]Saure A, Teravainen T, et al. The effect of synthetic gestagens on progesterone formation in vitro in human placenta of early pregnancy. J Reprod Fertil. 1977 Nov;51(2):369-73.

[3]Li Q, Li C, Jin H. Efficacy of allylestrenol combined with ritodrine on threatened premature labor and its influence on inflammatory factors in peripheral blood. Exp Ther Med. 2020 Feb;19(2):907-912

[4]Kohri K, Kurita T, Iguchi M, Kataoka K. [Clinical effects of allylestrenol on prostatic hypertrophy]. Hinyokika Kiyo. 1986 Mar;32(3):486-92. Japanese

[5]Noguchi K, Harada M, Masuda M, Takeda M, Kinoshita Y, Fukushima S, Miyai K, Fukuoka H, Hosaka M. Clinical significance of interruption of therapy with allylestrenol in patients with benign prostatic hypertrophy. Int J Urol. 1998 Sep;5(5):466-70

Allylestrenol 实验方案

计算器
存储液制备 1mg 5mg 10mg

1 mM

5 mM

10 mM

3.33mL

0.67mL

0.33mL

16.64mL

3.33mL

1.66mL

33.28mL

6.66mL

3.33mL

Allylestrenol 技术信息

CAS号432-60-0
分子式C21H32O
分子量 300.478
别名 烯丙雌醇
运输蓝冰
存储条件

In solvent -20°C:3-6个月-80°C:12个月

Pure form Sealed in dry,Room Temperature

溶解方案 请根据您的动物给药指南选择适当的溶解方案。
以下溶解方案都请先按照体外实验的方式配制澄清的储备液,再依次添加助溶剂:
——为保证实验结果的可靠性,澄清的储备液可以根据储存条件,适当保存;体内实验的工作液,建议现用现配,当天使用; 以下溶剂前显示的百分比是指该溶剂在终溶液中的体积占比;如在配制过程中出现沉淀、析出现象,可以通过加热和/或超声的方式助溶
方案一
方案二
动物实验配方
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