货号:A550852
同义名:
乳酸依沙吖啶一水物;利凡诺
/ Ethacridine lactate monohydrate; Acrinol monohydrat
Acrinol Monohydrate是一种抗菌剂和流产剂,主要用于抗革兰氏阳性细菌,且作为聚 (ADP-核糖) 糖基水解酶(PARG)抑制剂。
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描述 | Ethacridine (Lactate Monohydrate) is used as a topical antiseptic as well as for second-trimester abortion. And ethacridine is an inhibitor of poly (ADP-ribose) glycohydrolase (PARG) and an activator of the transcriptional coactivator with PDZ-binding motif (TAZ). Ethacridine elicits apoptotic cell death in thyroid cancer cells and promotes differentiation in a subset of thyroid follicular cells[3]. Extra-amniotic ethacridine lactate instillation alone and intracervical PGE2 (prostaglandin E2) gel application are effective and safe methods for second trimester abortion[4]. Mifepristone combined with ethacridine lactate is safe and effective for patients with low placentation or/and prior cesarean in the second-trimester pregnancy termination[5]. |
计算器 | ||||
存储液制备 | ![]() |
1mg | 5mg | 10mg |
1 mM 5 mM 10 mM |
2.77mL 0.55mL 0.28mL |
13.84mL 2.77mL 1.38mL |
27.67mL 5.53mL 2.77mL |
CAS号 | 6402-23-9 |
分子式 | C18H23N3O5 |
分子量 | 361.39 |
SMILES Code | NC1=CC2=NC3=CC=C(OCC)C=C3C(N)=C2C=C1.CC(O)C(O)=O.[H]O[H] |
MDL No. | MFCD00149646 |
别名 | 乳酸依沙吖啶一水物;利凡诺;乳酸依沙吖啶 一水合物 ;Ethacridine lactate monohydrate; Acrinol monohydrat; Ethodin; Rivanol monohydrate; Ethacridine(lactate monohydrate) |
运输 | 蓝冰 |
InChI Key | NYEPHMYJRNWPLA-UHFFFAOYSA-N |
Pubchem ID | 165457 |
存储条件 |
In solvent -20°C:3-6个月-80°C:12个月 Pure form Sealed in dry,2-8°C |
溶解方案 |
DMSO: 105 mg/mL(290.54 mM),注意:DMSO长时间开封后,会吸水并导致溶解能力下降,请避免使用长期开封的DMSO H2O: 2 mg/mL(5.53 mM),配合低频超声助溶 |