ATP | Adenosine triphosphate;Adenosine 5'-triphosphate;Triphosphoric acid adenosine ester;Triphosphaden;Atipi;Ara-ATP | 腺苷三磷酸

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三磷酸腺苷 /ATP {[allProObj[0].p_purity_real_show]}

货号：A160197 同义名： 腺苷三磷酸 / Adenosine triphosphate;Adenosine 5'-triphosphate

ATP is a central component of energy storage and metabolism in vivo, provides the metabolic energy to drive metabolic pumps and serves as a coenzyme in cells.

ATP 化学结构
CAS号：56-65-5

ATP 3D分子结构
CAS号：56-65-5

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ATP 纯度/质量文件产品仅供科研

货号：A160197 标准纯度： {[allProObj[0].p_purity_real_show]} 产品说明书

批次查询：批次纯度: COA SDS NMR HPLC CNMR LC-MS

全球学术期刊中引用的产品: • ACS Appl. Nano Mater., 2025. Ambeed. [ A188026 ]; • Eur. J. Clin. Microbiol. Infect. Dis., 2025. Ambeed. [ A151161 ]; • JJC, 2025, 20(Special Issue)): 27-39. Ambeed. [ A713856 ]; • bioRxiv, 2025. Ambeed. [ A538667 , A714873 , A126729 , A126049 , A446054 ]; • Nature Communications, 2025, 16, 1871. Ambeed. [ A508148 ]; 更多 >

ATP 生物活性

描述

Adenosine 5'-triphosphate (ATP) is a crucial component of energy storage and metabolism within the body. It not only provides the metabolic energy required for operating metabolic pumps but also acts as a coenzyme in various cellular processes. Additionally, ATP plays a significant role as an endogenous signaling molecule in immune responses and inflammation^[1].^[2].

体内研究

Furthermore, ATP induces the secretion of inflammatory cytokines and recruits neutrophils in vivo, enhancing immune responses^[4].

体外研究

When combined with LPS (1 μg/mL) at a concentration of 5 mM for one hour, ATP exhibits a synergistic effect on the activation of the NLRP3 inflammasome in human gingival fibroblasts (HGFs)^[3].

At a concentration of 2 mM, ranging from 0.5 to 24 hours, ATP triggers the secretion of IL-1β, KC, and MIP-2 from bone marrow-derived macrophages (BMDMs) in a manner dependent on caspase-1 activation^[4].

ATP also facilitates neutrophil chemotaxis in vitro and protects mice against bacterial infections when administered intraperitoneally at a dose of 50 mg/kg^[4].

ATP 参考文献

[1]Swennen EL, et al. Immunoregulatory effects of adenosine 5'-triphosphate on cytokine release from stimulated whole blood. Eur J Immunol. 2005 Mar;35(3):852-8.

[2]M J L Bours, et al. Adenosine 5'-triphosphate and adenosine as endogenous signaling molecules in immunity and inflammation. Pharmacol Ther. 2006 Nov;112(2):358-404.

[3]Shuo Xu, et al. Doxycycline inhibits NAcht Leucine-rich repeat Protein 3 inflammasome activation and interleukin-1β production induced by Porphyromonas gingivalis-lipopolysaccharide and adenosine triphosphate in human gingival fibroblasts. Arch Oral Biol. 2019 Nov;107:104514.

[4]Yang Xiang, et al. Adenosine-5'-Triphosphate (ATP) Protects Mice against Bacterial Infection by Activation of the NLRP3 Inflammasome. PLoS One. 2013; 8(5): e63759.

ATP 实验方案

计算器

存储液制备

1mg

5mg

10mg

1 mM

5 mM

10 mM

1.97mL

0.39mL

0.20mL

9.86mL

1.97mL

0.99mL

19.72mL

3.94mL

1.97mL

ATP 技术信息

CAS号	56-65-5
分子式	C₁₀H₁₆N₅O₁₃P₃
分子量	507.18

别名	腺苷三磷酸 ;Adenosine triphosphate;Adenosine 5'-triphosphate;Triphosphoric acid adenosine ester;Triphosphaden;Atipi;Ara-ATP
运输	蓝冰

存储条件

In solvent -20°C:3-6个月-80°C:12个月

Pure form Keep in dark place,Inert atmosphere,Store in freezer, under -20°C

溶解方案

细胞实验：

H₂O: 100 mg/mL(197.17 mM)

动物实验：配制的工作液建议现用现配，短期内尽快用完。以下溶剂前显示的百分比是指该溶剂在终溶液中的体积占比；如在配制过程中出现沉淀、析出现象，可以通过加热和/或超声的方式助溶。

方案一

动物实验配方

摩尔计算器

计算溶液所需的质量，体积或浓度。 Ambeed 摩尔浓度计算器基于以下方程式：

浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)=质量 (g)

浓度

体积

分子量

质量

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三磷酸腺苷 /ATP {[allProObj[0].p_purity_real_show]}

ATP 纯度/质量文件 产品仅供科研

全球学术期刊中引用的产品

ATP 质控信息

ATP 生物活性

ATP 参考文献

ATP 实验方案

ATP 技术信息

最近浏览的产品

大规格询价

摩尔计算器

靶点

总药量计算器

工作液计算器

细胞研究

临床研究

确认信息

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ATP 纯度/质量文件产品仅供科研