There will be a HazMat fee per item when shipping a dangerous goods. The HazMat fee will be charged to your UPS/DHL/FedEx collect account or added to the invoice unless the package is shipped via Ground service. Ship by air in Excepted Quantity (each bottle), which is up to 1g/1mL for class 6.1 packing group I or II, and up to 25g/25ml for all other HazMat items.
Type
HazMat fee for 500 gram (Estimated)
Excepted Quantity
USD 0.00
Limited Quantity
USD 15-60
Inaccessible (Haz class 6.1), Domestic
USD 80+
Inaccessible (Haz class 6.1), International
USD 150+
Accessible (Haz class 3, 4, 5 or 8), Domestic
USD 100+
Accessible (Haz class 3, 4, 5 or 8), International
1-(3-Dimethylaminopropyl)-3-ethylcarbodiimide hydrochloride functions as a carbodiimide reagent capable of forming nucleic acids and compounds with amide bonds. It acts as a condensing and dehydrating agent, accelerating the formation of esters, amides, and peptides, frequently employed in the synthesis of polynucleotides, anhydroxydation, lactonization, and esterification[1].[2].
体外研究
1-(3-Dimethylaminopropyl)-3-ethylcarbodiimide hydrochloride (EDC•HCl) is particularly effective in forming amide bonds (peptide bonds) within aqueous environments[1].
1-(3-Dimethylaminopropyl)-3-ethylcarbodiimide hydrochloride (EDC•HCl) is extensively applied in various scientific methods, including the preparation of polyaniline-carbon nanotube composites for cholesterol biosensors, precolumn derivatization of aliphatic amines for HPLC, creating molecular beacons for DNA research, developing sensors for calcium detection, determining carboxylic acids fluorescently, and performing solid-phase microsequencing of peptides[2].
As an inhibitor, 1-(3-Dimethylaminopropyl)-3-ethylcarbodiimide hydrochloride (EDC•HCl) targets aminoaldehyde dehydrogenase (AMADH), though its effect on glutamate decarboxylase (GAD) is minimal[3].
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