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SJFα is a PROTAC selectively targeting on p38α, consist of a warhead of foretinib linked to VHL-recruiting ligand.
SJFδ is a PROTAC selectively targeting on p38δ, consist of a warhead of foretinib linked to VHL-recruiting ligand. SJFδ exhibited DC50/Dmax values of 79.2nM/98.4% and 45.9nM/34.5% for degradation of p38δ and p38α, respectively.
Tags: p38/PROTAC | PROTAC功能分子 | PROTAC Molecule | p38/PROTAC 相关产品
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