Lopinavir（ABT-378）是一种高效选择性的HIV-1蛋白酶抑制剂，对野生型和突变型HIV蛋白酶的Ki值在1.3至3.6 pM之间。其作用是阻止HIV-1的成熟，从而阻止其感染性。Lopinavir还表现出对SARS-CoV 3CLpro的抑制作用，IC50为14.2 μM。

Pneumocandin B0 is used to synthesize caspofungin. It is a strong antifungal working by inhibiting the synthesis of β-(1→3)-D-glucan, which is a fundamental component in most cell walls

Daptomycin is a lipopeptide antimicrobial agent with activity against Gram-positive organisms, including multi-resistant strains.

Ritonavir is both an HIV protease inhibitor and a Cytochrome P450 3A inhibitor.

Cyclosporine A is an immunosuppressive agent, binds to the cyclophilin and then inhibits calcineurin with IC50 of 7 nM.