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全部(21) Modulator(1) Agonist(1)
LM11A-31 2HCl是一种非肽 p75NTR(神经营养蛋白受体 p75)调节剂,作为口服有效的 proNGF 拮抗剂,具有良好的血脑屏障通透性,能阻断 p75 介导的细胞死亡。
SBI-553 is a potent, brain-penetrant and allosteric modulator of NTR1 with EC50 of 0.34 μM.
ML314 is a potent molecule agonist of NTR1 (EC50 = 1.9 μM) and shows good selectivity against NTR2 and GPR35, but did not stimulate Ca2+ mobilization.
PD 90780 is a non-peptide inhibitor of nerve growth factor (NGF) binding to p75NTR receptor. It inhibits NGF-p75 NTR interaction with IC50s values of 23.1 µM and 1.8 µM in PC12 cells and PC12 nnr5 cells, respectively.
Neurotensin, a potent hypothalamic peptide neurotransmitter, is an endogenous anti-psychotic compound which has a high affinity for neurotensin receptors.
JMV 449 is a potent, metabolically stable neurotensin receptor agonist peptide.
Kinetensin is endogenous neurotensin-like peptide originally isolated from pepsin-treated human plasma. It can induce histamine release from rat peritoneal mast cells in vitro.
Neurotensin Fragment 8-13 is the smallest active fragment of neurotensin which is a potent cellular mitogen for various colorectal and pancreatic cancers which possess high-affinity neurotensin receptors (NTR).
Xenopsin is the neurotensin-like octapeptide from Xenopus skin at the carboxyl terminus of its precursor.
Tags: 神经降压素受体 | Neurotensin Receptor | G蛋白偶联受体/G蛋白 | GPCR/G Protein | 神经信号通路 | Neuronal Signaling | 神经降压素受体 相关产品
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